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Development of short-range irradiation technique of Spot-Scanning proton therapy

Research Project

Project/Area Number 25861048
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionNational Institute of Radiological Sciences (2014-2015)
Hokkaido University (2013)

Principal Investigator

Toramatsu Chie  国立研究開発法人放射線医学総合研究所, 重粒子医科学センター, 主任研究員 (90421825)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords陽子線治療 / スキャニング照射 / 粒子線治療 / 認証システム / 短飛程照射 / スポットスキャニング / 低エネルギー照射
Outline of Final Research Achievements

In scanned-beam proton therapy, the lateral and longitudinal size and the minimum achievable range, are influenced by beam optics, scattering media and drift spaces in the treatment unit. In this study, methods for adjusting the lateral and longitudinal spot size were investigated. Two methods were nvestigated; one is the method of utilizing downstream plastic pre-absorbers located near a patient and the other is the method of utilizing beam shaper/filter/absorbers in the treatment head. The spot size adjustment was characterized using Monte Carlo simulations of a modified commercial scanned-beam treatment head. Depend on this result, pre-absorbers were designed for clinical use to treat shallow seated tumor. And novel shape ripple filters were studied which are expected to have improved manufacturability. These findings suggest that this spot adjustment method may improve the quality of spot-canned proton treatments.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (10 results)

All 2016 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (8 results) (of which Invited: 2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] What is the appropriate size criterion for proton radiotherapy for hepatocellular carcinoma? A dosimetric comparison of spot-scanning proton therapy versus intensity-modulated radiation therapy2013

    • Author(s)
      Chie Toramatsu,
    • Journal Title

      Radiation Oncology

      Volume: 8 Issue: 1 Pages: 48-48

    • DOI

      10.1186/1748-717x-8-48

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] comissioning of spot scanning particle therapy system2016

    • Author(s)
      高柳泰介
    • Organizer
      PTCOG 2016
    • Place of Presentation
      Prague
    • Year and Date
      2016-05-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] A novel shape ridge filter for particle beam therapy2016

    • Author(s)
      高柳泰介
    • Organizer
      医学物理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-04-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Comissioning of Spot-Scanning Particle Therapy System2014

    • Author(s)
      寅松千枝
    • Organizer
      重粒子線医工連携セミナー
    • Place of Presentation
      群馬大学重粒子線医学センター
    • Year and Date
      2014-04-24
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 陽子線治療システムのコミッショニング報告2014

    • Author(s)
      寅松千枝
    • Organizer
      日本医学物理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 陽子線治療システムビーム試験の報告2014

    • Author(s)
      寅松千枝
    • Organizer
      日本医学物理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Clinical Commissioning of Hokkaido University Hospital Proton Therapy Center2014

    • Author(s)
      Chie Toramatsu, Taeko Matsuura, Seishin Takao, Hideaki Nihongi, Takanori Yamada,Naoki Miyamoto, Shinichi Shimizu, Kikuo Umegaki and Hiroki Shirato
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 北海道大学病院陽子線治療システムのコミッショニング報告と現状2014

    • Author(s)
      寅松千枝
    • Organizer
      重粒子線医工連携セミナー
    • Place of Presentation
      群馬大学重粒子医科学センター(前橋市)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Clinical Commissioning of Hokkaido University Hospital Proton Therapy Center2014

    • Author(s)
      Chie Toramatsu, Taeko Matsuura, Seishin Takao, Hideaki Nihongi, Takanori Yamada,Naoki Miyamoto, Shinichi Shimizu, Kikuo Umegaki and Hiroki Shirato
    • Organizer
      PTCOG 53
    • Place of Presentation
      Shanghai International Convention Center(Shanghai, China)
    • Related Report
      2013 Research-status Report
  • [Patent(Industrial Property Rights)] 粒子線治療システムおよびリッジフィルタならびにリッジフィルタの製造方法2013

    • Inventor(s)
      寅松千枝,松浦妙子,宮本直樹,二本木英明,梅垣菊男,平田雄一
    • Industrial Property Rights Holder
      寅松千枝,松浦妙子,宮本直樹,二本木英明,梅垣菊男,平田雄一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-260896
    • Filing Date
      2013-12-18
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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