| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We considered whether it was able to foresee esophageal varices development to detect change in left gastric vein (LGV) direction by visualizing LGV with flow direction by non-contrast-enhanced MRA. Firstly, LGV with flow direction could be selectively visualized by non-contrast-enhanced MRA using bSSFP sequence with Time-SLIPs. Secondly, LGV flow velocity could be measured by MRI of phase contrast imaging using non-contrast-enhanced MRA. We hypothesized that, as portal vein pressure increases, LGV flow in the PV system transforms to a portal systemic shunt by changing the flow direction from normal (toward the liver: hepatopetal) to reversed (away from the liver: hepatofugal). However, LGV flow was stagnant or hepatofugal transiently in part of healthy subjects with normal portal pressure. So, it is possible that it cann’t foresee esophageal varices development to only detect change in LGV direction.
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