Investigation of iodine and cesium radiation doze by the last nuclear medicine technique.

• Project/Area Number: 25861094
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Osaka University
• Principal Investigator: KANAI Yasukazu 大阪大学, 医学(系)研究科(研究院), 寄附講座助教 (60397643)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 放射性ヨウ素 / 核医学 / 内部被曝 / PET / 体内動態

Outline of Final Research Achievements

We comfirm the pharmacokinetics of radioactive iodine in mouse or rat. The pharmacokinetics of radioactive iodine in mouse or rat is different by the administration methods. In mouse, radioactive iodine accumlation at thyroid gland is different between oral administration and Intravenus injection.
We succeeded to investigate the pharmacokinetics of radioactive iodine in mouse or rat by gamma camera and PET.By this study, we think to guess the exposure amount by the radioisotope uptaken in the human body by the latest nuclear medicine techniques such as γ camera .