| Project/Area Number |
25861101
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Hyogo Medical University (2014)
Kobe University (2013) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | MRI / テンソル画像 / 前立腺癌 / 陰茎海綿体神経 / 前立腺全摘術 / 勃起障害 / 前立腺がん / 核磁気共鳴画像（MRI）） |
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| Outline of Final Research Achievements |
I performed the experiment by volunteers using 3.0-Tesla MRI and planned the optimization of the scanning parameter of the diffusion tensor imaging (DTI) technique for the purpose of the depicting periprostatic nerve fibers. I evaluated whether the DTI can visualize changes in the numbers of periprostatic nerve fibers before and after nerve-sparing and non-nerve-sparing prostatectomy in fifty-two prostate cancer patients who underwent DTI before and after prostatectomy. After non-nerve-sparing prostatectomy, the numbers of tracts were significantly decreased However, after nerve-sparing prostatectomy, the numbers of tracts were not changed significantly. The result is accepted in a journal (Clin Imaging 2014;38:302-6). I evaluated whether the DTI can visualize periprostatic nerve fibers in patients who had underwent non-nerve-sparing prostatectomy, with the reference of pathological specimen, and I confirmed that DTI may be feasible for visualization of periprostatic nerve fibers.
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