Research Project
Grant-in-Aid for Young Scientists (B)
The purpose of this study was to evaluate nuclear factor-kappaB (NF-KappaB) as a marker of radioresistance in oropharyngeal carcinomas. Immunohistochemistry was performed using pretreatment biopsy specimen to evaluate the presence of NF-kappaB expression in these tumor. Similar experiments was performed in subgroups of recurrent tumor specimens. The prognostic value of other molecular markers such as Bcl-2 and epidermal growth factor (EGF) receptor were also evaluated and compared with NF-kappaB. NF-kappaB expression in pretreatment tumors correlated with local tumor control. NF-kappaB expression may be a novel marker of radioresistance in oropharyngeal carcinomas. Bcl-2 and EGF receptor expression did not correlate with radioresistance.
All 2015 2014 2013
All Journal Article (16 results) (of which Peer Reviewed: 6 results, Open Access: 3 results, Acknowledgement Compliant: 1 results) Presentation (45 results) Book (1 results)
Jpn J Clin Oncol
Volume: 45 Issue: 3 Pages: 248-55
10.1093/jjco/hyu203
Int J Radiat Oncol Biol Phys
Volume: 90(5) Issue: 5 Pages: 1177-1185
10.1016/j.ijrobp.2014.07.048
PLoS One
Volume: 9(5) Issue: 5 Pages: e96999-e96999
10.1371/journal.pone.0096999
120005603819
日本癌治療学会誌
Volume: 49 Pages: 2659-2659
頭頸部癌
Volume: 40 Pages: 265-265
Volume: 40 Pages: 264-264
Volume: 40 Pages: 238-238
Volume: 40 Pages: 155-155
がん看護
Volume: 19 Pages: 319-323
40020020751
Japanese Journal of Radiology
Volume: 32 Pages: 42-42
Volume: 32 Pages: 37-37
Volume: 32 Pages: 36-36
Volume: 32 Pages: 30-30
Med Dosim.
Volume: 39(1) Issue: 1 Pages: 31-3
10.1016/j.meddos.2013.09.001
日本消化器病学会雑誌
Volume: 110 Pages: 2073-2080
130003383326
癌と化学療法
Volume: 40 Pages: 1856-1858