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Study on optimization of the segmental acquisition method to improve the visualization of the cancer lesion in the nuclear medicine diagnosis.

Research Project

Project/Area Number 25861115
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionTsukuba International University (2014-2016)
Ibaraki Prefectural University of Health Science (2013)

Principal Investigator

tsuda keisuke  つくば国際大学, 医療保健学部, 講師(移行) (00598146)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords核医学検査 / 分割収集法 / FDG-PET検査 / 呼吸運動 / 放射線治療 / 定量性
Outline of Final Research Achievements

In this study, we aimed at the optimization of the segmental acquisition method to improve the visualization of the cancer lesion in the nuclear medicine diagnosis. We evaluated the usefulness of the segmental acquisition method in clinical FDG-PET tests for rectal cancer. As for the segmental acquisition method, detection of cancer lesions and image quality were significantly superior to the conventional continuous acquisition method, and clinical usefulness was suggested. Then, we evaluated the effects of respiratory motion on the quantitatively of pulmonary nodules on FDG-PET test by experiments using a dynamic thorax phantom. Based on the results of these experiments, we derived a new correction method for the quantitatively of pulmonary nodules on FDG-PET test. Our newly proposed methods could correct the decrease of counts of pulmonary nodules due to partial volume effects and motion effects with acceptable errors.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (19 results)

All 2017 2016 2015 2014 2013

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (17 results)

  • [Journal Article] Characteristic X-ray imaging for palliative therapy using strontium-89 chloride: understanding the mechanism of nuclear medicine imaging of strontium-89 chloride2017

    • Author(s)
      Yoshiki Owaki, Kazumasa Inoue, Hiroto Narita, Keisuke Tsuda, Masahiro Fukushi
    • Journal Title

      Radiological Physics and Technology

      Volume: 印刷中 Issue: 2 Pages: 227-233

    • DOI

      10.1007/s12194-016-0388-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 核医学検査での被ばく評価2016

    • Author(s)
      津田啓介
    • Journal Title

      放射線防護部会誌

      Volume: 43 Pages: 16-20

    • Related Report
      2016 Annual Research Report
  • [Presentation] 核医学検査での被ばく評価2016

    • Author(s)
      津田啓介
    • Organizer
      第44会日本放射線技術学会秋季学術大会
    • Place of Presentation
      大宮
    • Related Report
      2016 Annual Research Report
  • [Presentation] Gaussian filterがPET画像濃度の描出能精度に及ぼす影響の評価2016

    • Author(s)
      相良裕亮,橋本直起,小山和也,小坂徹,白石貴博,清水秀雄,津田啓介
    • Organizer
      第44会日本放射線技術学会秋季学術大会
    • Place of Presentation
      大宮
    • Related Report
      2016 Annual Research Report
  • [Presentation] PET検査における不均一腫瘍モデルを用いた至適画像再構成条件の検討2016

    • Author(s)
      橋本直起,相良裕亮,小山和也,小坂徹,白石貴博,清水秀雄,津田啓介
    • Organizer
      第44会日本放射線技術学会秋季学術大会
    • Place of Presentation
      大宮
    • Related Report
      2016 Annual Research Report
  • [Presentation] development of metabolic tumor volume measurement based on suvpeak2015

    • Author(s)
      K. Koyama, T. Mitsumoto, K. Inoue, K. Tsuda, K. Kotaka, K. Yoshikawa, K. Hatano, M. Fukushi
    • Organizer
      28th Annual EANM Congress
    • Place of Presentation
      Hamburg, Germany
    • Year and Date
      2015-10-11
    • Related Report
      2015 Research-status Report
  • [Presentation] ドーズキャリブレーター~まさか、買ったままでは!?~2015

    • Author(s)
      津田啓介
    • Organizer
      PETサマーセミナー2015in東京ベイ
    • Place of Presentation
      東京
    • Year and Date
      2015-09-05
    • Related Report
      2015 Research-status Report
  • [Presentation] PET-CT検査におけるCTとPET画像の位置ずれによる定量性への影響2015

    • Author(s)
      青木沙起、三本拓也、小山和也、小坂徹、青山里愛、遠山尚紀、小高喜久雄、幡野和男、津田啓介、井上一雅、福士政広
    • Organizer
      日本保健物理学会第48回研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-03
    • Related Report
      2015 Research-status Report
  • [Presentation] ドーズキャリブレーターの保守点検について2015

    • Author(s)
      津田啓介
    • Organizer
      第15回日本核医学会春季大会
    • Place of Presentation
      船堀
    • Year and Date
      2015-04-26
    • Related Report
      2015 Research-status Report
  • [Presentation] A new quantitative correction method for pulmonary nodules on chest FDG-PET2014

    • Author(s)
      Tsuda K, Koyama K, Takanashi T, Tsushima H, Kurashima S, Aoki S, Inoue K, Fukushi M, Fujii H
    • Organizer
      4th annual international ASNMT conference
    • Place of Presentation
      Osaka
    • Year and Date
      2014-11-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Experimental evaluation of the usefulness of chest FDG-PET acquisition under the tachypneic condition for pulmonary nodule detection2014

    • Author(s)
      Tsuda K, Aoki S, Koyama K, Oku Y, Takeda A, Tsushima H, Mitsumoto T, Inoue K, Fukushi M, Fujii H
    • Organizer
      Society of Nuclear Medicine 2014 Annual Meeting
    • Place of Presentation
      St. Louis, MO, USA
    • Year and Date
      2014-06-10
    • Related Report
      2014 Research-status Report
  • [Presentation] Segmental acquisition method for rectal cancer in FDG-PET/CT tests: Analysis of 20 patients2013

    • Author(s)
      Tsuda K, Koyama K, Iwabuchi Y, Suzuki T, Toya K, Hirayama A, Tsushima H, Fukushi M, Moriyama N, Fujii H
    • Organizer
      Society of Nuclear Medicine 2013 Annual Meeting
    • Place of Presentation
      Vancouver
    • Related Report
      2013 Research-status Report
  • [Presentation] 低酸素PET/CT検査における呼吸同期の基礎的検討2013

    • Author(s)
      岩下寛志,小山和也,青柳俊,根本幸一,小島良紀,津田啓介,藤井博史
    • Organizer
      第52回千葉核医学研究会
    • Place of Presentation
      千葉
    • Related Report
      2013 Research-status Report
  • [Presentation] 62Cuを用いた低酸素PET/CT検査における呼吸同期収集法の有用性2013

    • Author(s)
      岩下寛志,小山和也,津田啓介,青柳俊,根本幸一,小島良紀,藤井博史
    • Organizer
      日本放射線技術学会第41回秋季学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] FDG-PET検査における胸部結節性病変の頻呼吸下撮像法の検討2013

    • Author(s)
      青木沙起,津田啓介,倉嶋汐里,小山和也,青柳俊,岩下寛志,根本幸一,奥洋平,武田篤也,對間博之,平山昭,福士政広,藤井博史
    • Organizer
      第33回日本核医学技術学会総会学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] FDG-PET検査における胸部結節性病変の呼吸運動の影響を考慮した新たな定量値補正法の検討2013

    • Author(s)
      倉嶋汐里,津田啓介,青木沙起,小山和也,青柳俊,岩下寛志,根本幸一,奥洋平,武田篤也,對間博之,平山昭,福士政広,藤井博史
    • Organizer
      第33回日本核医学技術学会総会学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 胸部PET/CT検査時の呼吸性移動を考慮した定量値補正法の開発2013

    • Author(s)
      小山和也,青柳俊,岩下寛志,田中史弥,根本幸一,小島良紀,青木沙起,倉嶋汐里,奥洋平,武田篤也,津田啓介,藤井博史
    • Organizer
      第33回日本核医学技術学会総会学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 胸部FDG-PET/CT検査における新たな定量値補正法の検討2013

    • Author(s)
      青柳俊,小山和也,岩下寛志,根本幸一,青木沙起,倉嶋汐里,津田啓介
    • Organizer
      第33回日本核医学技術学会総会学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 呼吸同期撮像の技術的検討2013

    • Author(s)
      津田啓介
    • Organizer
      第3回GE Metropolitan Area PET Users Meeting
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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