Development of advanced data acquisition methods for quantitative SPECT

• Project/Area Number: 25861131
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyoto College of Medical Science
• Principal Investigator: MATSUMOTO Keiichi 京都医療科学大学, 公私立大学の部局等, 講師 (60393344)
• Research Collaborator: FUJITA Masaki ; MURAKAMI Mikoto ; WADA Ryota
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: SPECT / 非対称法 / 補間投影データ法 / 逐次近似画像再構成 / 緩和係数 / 画像再構成 / 反復法 / 二検出器ガンマカメラ装置 / 二検出器型ガンマカメラ装置 / 補間

Outline of Final Research Achievements

The purpose of this study was to develop a Hybrid SPECT reconstruction method by a combination of the asymmetric SPECT acquisition, IPDE (Interpolated Projection Data Estimation) method and modified DRAMA (Dynamic RAMLA) reconstruction algorithm. A Hybrid SPECT reconstruction method was evaluated to a two-dimensional Shepp-Logan head numerical phantom with statistical noise and a 3-D brain phantom. Quality of the reconstructed images was evaluated in terms of mean structural similarity (MSSIM) values. The Hybrid SPECT reconstruction method showed faster resolution recovery with lower noise than the asymmetric SPECT acquisition and IPDE method and yielded acceptable images in 2 or 3 iteration. The sensitivity of a gamma camera was also maintained virtually constant during the 3 years.

Research Products

• [Journal Article] SPECT・PETの画像再構成法（逐次近似法） (2015)
  • Author(s): 松本圭一
  • Journal Title: 日本放射線技術学会雑誌 Volume: 71 Pages: 66-71
• [Journal Article] SPECT・PETの画像再構成法（FBP法） (2014)
  • Author(s): 松本圭一
  • Journal Title: 日本放射線技術学会雑誌 Volume: 70 Pages: 1496-1504
• [Journal Article] がんFDG-PET/CT撮像法ガイドライン第2版 (2014)
  • Author(s): 福喜多博義, 織田圭一, 白石貴博, 鈴木一史, 西田広之, 松本圭一, 寺内隆司, 坂本攝, 西尾知之, 井狩彌彦, 千田道雄, 木村裕一, 大﨑洋充, 島田直毅
  • Journal Title: 核医学技術 Volume: 33 Pages: 377-420
• [Journal Article] 二種類のFDG-PET ガイドラインに対応した解析ソフトウェアパッケージの開発 (2013)
  • Author(s): 松本圭一, 遠藤啓吾
  • Journal Title: 日本放射線技術学会雑誌 Volume: 69 Pages: 648-654
  • NAID: 10031174160
  • Peer Reviewed
• [Presentation] Hybrid SPECT画像再構成法に関する研究 (2015)
  • Author(s): 松本圭一, 高橋康幸, 村瀬研也, 高木昭浩, 和田康弘, 遠藤啓吾
  • Organizer: 第55回日本核医学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2015-11-05
• [Presentation] Development of advanced data acquisition methods for quantitative single photon emission computed tomography (2015)
  • Author(s): Matsumoto K, Takahashi Y, Takaki A, Murase K, Wada Y, Watanabe Y, Endo K
  • Organizer: Annual Congress of the European Association of Nuclear Medicine 2015
  • Place of Presentation: Hamburg
  • Year and Date: 2015-10-10
  • Int'l Joint Research
• [Presentation] 核医学画像の画像評価法 (2015)
  • Author(s): 松本圭一
  • Organizer: 第43回日本放射線技術学会秋季学術大会
  • Place of Presentation: 金沢
  • Year and Date: 2015-10-08
• [Presentation] An attenuation correction method of preclinical multipinhole SPECT system using modified correction matrix method (2014)
  • Author(s): Matsumoto K, Magata Y, Wada Y, Murase K, Watanabe Y, Endo K
  • Organizer: Annual Congress of the European Association of Nuclear Medicine 2014
  • Place of Presentation: Gothenburg
  • Year and Date: 2014-10-18 – 2014-10-22
• [Presentation] Usefulness of CT iterative reconstruction method for low-dose CT attenuation correction on the accuracy of PET image in obesity phantom study (2013)
  • Author(s): Matsutomo N, Onishi H, Nagaki A, Matsumoto K, Sasaki M
  • Organizer: Society of Nuclear Medicine and Molecular Imaging 2013 Annual Meeting
  • Place of Presentation: Vancouver
• [Presentation] QA/QC：PET装置、周辺機器の精度管理 (2013)
  • Author(s): 松本圭一
  • Organizer: PETサマーセミナー2013 in加賀百万石
  • Place of Presentation: 金沢
  • Invited
• [Presentation] デリバリーFDG-PET/CT検査におけるPET画像の画質標準化についての検討 (2013)
  • Author(s): 清水敬二, 松本圭一, 四井哲士, 三船祐輔, 日野恵, 千田道雄, 山本誠一
  • Organizer: PETサマーセミナー2013 in加賀百万石
  • Place of Presentation: 金沢
• [Presentation] Variability in PET quantitation within a multicenter studies in Japan (2013)
  • Author(s): Matsumoto K, Suzuki K, Fukukita H, Ikari Y, Oda K, Kimura Y, Sakamoto S, Shimada N, Shiraishi T, Nishio T, Nishida H, Terauchi T, Senda M
  • Organizer: Annual Congress of the European Association of Nuclear Medicine 2013
  • Place of Presentation: Lyon
• [Presentation] がんFDG PET/CT撮像法標準化におけるSUVの検証 (2013)
  • Author(s): 松本圭一, 福喜多博義, 鈴木一史, 西田広之, 井狩彌彦, 織田圭一, 木村裕一, 島田直毅, 白石貴博, 寺内隆司, 千田道雄
  • Organizer: 第53回日本核医学会学術総会
  • Place of Presentation: 福岡
• [Book] 新・医用放射線技術実験［基礎編］第3版 断層画像（Transmission CT・Emission CT画像） (2016)
  • Author(s): 松本圭一, 向井孝夫, 村瀬研也
  • Total Pages: 456
  • Publisher: 共立出版株式会社
• [Book] 図解診療放射線技術実践ガイド第3版 (2014)
  • Author(s): 遠藤啓吾編集
  • Total Pages: 1084
  • Publisher: 文光堂
• [Book] 診療放射線技師国家試験対策全科改訂11版 (2014)
  • Author(s): 西谷源展編著
  • Total Pages: 610
  • Publisher: 金芳堂
• [Book] 医用放射線辞典第5版 (2013)
  • Author(s): 医用放射線辞典編集委員会編
  • Total Pages: 765
  • Publisher: 共立出版
• [Remarks] 専任教員の研究業績
  • URL: http://www.kyoto-msc.jp/international/research.html
• [Remarks] 専任教員の研究業績
  • URL: http://www.kyoto-msc.jp/international/research.html