Identifying prediction marker for brain metastasis using brain seeking breast cancer cells

• Project/Area Number: 25861162
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General surgery
• Research Institution: Iwate Medical University
• Principal Investigator: ISHIDA kazushige 岩手医科大学, 医学部, 助教 (80583541)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 乳癌 / 脳転移 / バイオマーカー / 新規バイオマーカー

Outline of Final Research Achievements

Eighteen candidate biomarkers were identified by gene expression analysis with twenty thousand human genome between MDA-MB231 and 231BR cells. Moreover, some gene mutations were identified by genome sequencing.

Research Products

• [Presentation] 脳転移指向性乳癌細胞株を用いた脳転移予測マーカー探索 (2014)
  • Author(s): 石田 和茂
  • Organizer: 第52回日本癌治療学会学術集会
  • Place of Presentation: 横浜
  • Year and Date: 2014-08-28 – 2014-08-30
• [Presentation] 脳転移指向性乳癌細胞株を用いた脳転移予測マーカー探索 (2014)
  • Author(s): 石田 和茂
  • Organizer: 第114回日本外科学会定期学術集会
  • Place of Presentation: 京都
  • Year and Date: 2014-04-03 – 2014-04-05
• [Presentation] 脳転移指向性乳癌細胞株を用いた脳転移予測マーカー探索 (2014)
  • Author(s): 石田和茂
  • Organizer: 第114回 日本外科学会定期学術集会
  • Place of Presentation: 京都府
• [Presentation] 脳転移指向性乳癌細胞株を用いた脳転移予測マーカー探索 (2014)
  • Author(s): 石田和茂
  • Organizer: 第11回 日本乳癌学会東北地方会
  • Place of Presentation: 宮城県
• [Presentation] 脳転移指向性乳癌細胞株を用いた脳転移予測マーカー探索 (2013)
  • Author(s): 石田和茂
  • Organizer: 第21回 日本乳癌学会学術集会
  • Place of Presentation: 静岡県