Circulating tumor cekks as an indipendent predictor of survival for advanced gastric cancer

Research Project

Project/Area Number	25861183
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Digestive surgery
Research Institution	Kyoto University
Principal Investigator	TSUNODA Shigeru 京都大学, 医学(系)研究科(研究院), 助教 (60597300)
Project Period (FY)	2013-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	末梢血循環癌細胞 / 胃癌 / .胃癌 / 末梢血中腫瘍細胞
Outline of Final Research Achievements	For primary gastric cancer to metastasize, it is necessary for tumor cells to circulate in the peripheral blood as a viable state. In this study, viable circulating tumor cells (CTCs) were successfully detected in nearly 40% of patients with highly advanced gastric cancer. Moreover, tumors of patients with positive CTCs were shown to progress earlier. Detecting CTCs can be clinically applied for selecting optimal patients for induction chemotherapy and would be useful for monitoring of therapeutic effect.

Report

(3 results)