Development of neuropathic pain cure using a nerve regeneration and a neurodifferentiate factor
| Project/Area Number |
25861357
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology
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| Research Institution | Gunma University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 神経障害性疼痛 / Notch Signal / Notch signal / Notchシグナル |
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| Outline of Final Research Achievements |
Overexpression of Notch signal reduce the survival rate of the middle stage (3-4 days) of the cells, but improvement of the survival rate by CNTF, EGF and BDNF was not recognized at the present time. We aimed to improve the survival rate by exposure to hypoxia and further investigated the cell viability in low oxygen environment at 18% and 15%, but improvement of cell viability in the hypoxic environment was observed There was not.
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Report
(5 results)
Research Products
(4 results)
