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Development of neuropathic pain cure using a nerve regeneration and a neurodifferentiate factor

Research Project

Project/Area Number 25861357
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Anesthesiology
Research InstitutionGunma University

Principal Investigator

SEKIMOTO KENICHI  群馬大学, 医学部附属病院, 助教 (90515090)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords神経障害性疼痛 / Notch Signal / Notch signal / Notchシグナル
Outline of Final Research Achievements

Overexpression of Notch signal reduce the survival rate of the middle stage (3-4 days) of the cells, but improvement of the survival rate by CNTF, EGF and BDNF was not recognized at the present time. We aimed to improve the survival rate by exposure to hypoxia and further investigated the cell viability in low oxygen environment at 18% and 15%, but improvement of cell viability in the hypoxic environment was observed There was not.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2017 2016 2013

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results) Book (1 results)

  • [Journal Article] Local anesthetic toxicity: acute and chronic management2017

    • Author(s)
      Kenichi Sekimoto, Maseru Tobe, and Shigeru saito
    • Journal Title

      Acute Medicine & Surgery

      Volume: - Issue: 2 Pages: 152-160

    • DOI

      10.1002/ams2.265

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 麻酔薬の幼若脳に与える影響2016

    • Author(s)
      関本 研一, 齋藤 繁
    • Journal Title

      麻酔

      Volume: 65増刊

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] 群馬大学医学部緩和ケアチーム介入症例におけるプレギャバリン使用症例の検討2013

    • Author(s)
      関本研一、三枝里江、齋藤繁
    • Organizer
      日本麻酔科学会 第60回学術集会
    • Place of Presentation
      札幌
    • Related Report
      2013 Research-status Report
  • [Book] 麻酔科医のための困った時の3分コンサルタント2016

    • Author(s)
      関本研一, 齋藤繁、稲田英一 編
    • Publisher
      克誠堂出版株式会社
    • Related Report
      2016 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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