Effect of amino acid administration on postoperative muscle atrophy

• Project/Area Number: 25861379
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Anesthesiology
• Research Institution: Kochi University
• Principal Investigator: YATABE Tomoaki 高知大学, 教育研究部医療学系, 助教 (60437720)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
• Keywords: 周術期栄養療法 / 周術期管理 / アミノ酸

Outline of Final Research Achievements

This study focused on relationship between amino acid intake and muscle atrophy.
First, we conducted systematic review for effect of amino acid and protein on outcome in critical ill patients because we estimated optimal dose of amino acid in accordance with studies of intensive care units. However, there was no study. Second, we reported that protein and amino acid effected on rehabilitation status.
This knowledge might contribute to further researches.

Research Products

• [Journal Article] Current status of studies about optimal composition of amino acid and protein for ICU patients: systematic review. (2014)
  • Author(s): Tamura T, Yatabe T, Yokoyama M, Nishimura M.
  • Journal Title: Anaesth Intensive Care Volume: 42 Pages: 806-7
  • Peer Reviewed
• [Presentation] Retrospective analysis of the relationship between amino acid and protein intake and rehabilitation status in critically ill patients. (2015)
  • Author(s): T Yatabe, T Tamura, I Miyajima, K Yamashita, M Yokoyama.
  • Organizer: 3rd SG-ANZICS Intensive Care Forum 2015
  • Place of Presentation: サンテックカンファレンス シンガポール（シンガポール）
  • Year and Date: 2015-04-24 – 2015-04-26
• [Presentation] Current status of studies in the world about optimal composition of the amino acid and protein for ICU patients: systematic review. (2014)
  • Author(s): T Tamura, T Yatabe, M Yokoyama, M Nishimura.
  • Organizer: ESICM 27th annual congress
  • Place of Presentation: バルセロナ国際会議場 バルセロナ（スペイン）
  • Year and Date: 2014-09-27 – 2014-10-01
• [Presentation] 早期経腸栄養・経口摂取 (2014)
  • Author(s): 矢田部 智昭, 横山 正尚
  • Organizer: 日本麻酔科学会第61回学術集会
  • Place of Presentation: 横浜（パシフィコ横浜）
  • Year and Date: 2014-05-15 – 2014-05-17