Elucidation of the cancer recurrence restraint mechanism of the epidural anesthesia
Project/Area Number |
25861400
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Anesthesiology
|
Research Institution | Keio University |
Principal Investigator |
|
Research Collaborator |
IGARASHI Toru
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 硬膜外麻酔 / がん抑制 / Th1/Th2バランス / Th17 / 炎症性サイトカイン / NK活性 |
Outline of Final Research Achievements |
We performed a study to search the change of a cancer recurrence and the perioperative function of immunity, based on the hypothesis ‘Epidural anesthesia maintains the function of natural killer cells and T cells, consequently suppress the cancer multiplication', using the rat long-term epidural anesthesia model which has been already established in our laboratory. We are not able to observe the influence that an epidural anesthesia gave Natural killer cell and T cell in this study. Further studies are warranted to clarify relationship between epidural anesthesia and cancer recurrence.
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Report
(3 results)
Research Products
(3 results)