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Molecular epidemiological survey of Human adenoviruses in sexually transmitted infections.

Research Project

Project/Area Number 25861458
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionNational Institute of Infectious Diseases

Principal Investigator

HANAOKA Nozomu  国立感染症研究所, その他部局等, 研究員 (00584517)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords性感染症 / 非クラミジア性非淋菌性尿道炎 / 病原体探索 / アデノウイルス / 非淋菌非クラミジア性尿道炎
Outline of Final Research Achievements

From 2013 to 2014, "Molecular epidemiological survey of Human adenoviruses (Ads) in sexually transmitted infections." was performed. In particular, we focused on “Urethritis” among STI (sexually transmitted infections) that recently reported adenovirus involvement. While research period, a collaboration system with urologic clinic was established as the basis for this study, comprehensive detection system for microorganism in urine was developed, And clinical surveillance for adenovirus in urealitis have been facilitated. Total of approximately 200 urine and gargle specimens from patients with urethritis and about 100 urine and gargle specimens from asymptomatic control were collected. Among them, from urine specimens of nonchlamydial nongonococcal urethritis. As results of screening, several Ad had been detected and isolated as statistically significant. According to genetically analysis of detected Ads, Ad56 type was the most numerous, followed by Ad37 type.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (13 results)

All 2014 2013 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results) Presentation (3 results) Remarks (4 results)

  • [Journal Article] A novel complex recombinant form of type 48-related human adenovirus species D isolated in Japan.2014

    • Author(s)
      Fujimoto T, Yamane S, Ogawa T, Hanaoka N, Ogura A, Hotta C, Niwa T, Chiba Y, Gonzalez G, Aoki K, Koyanagi KO, Watanabe H
    • Journal Title

      Jpn J Infect Dis.

      Volume: 67 Pages: 282-287

    • NAID

      130004757096

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Echovirus 3 as another enterovirus causing life-threatening neonatal fulminant hepatitis.2014

    • Author(s)
      Miyata I, Hanaoka N, Okabe N, Fujimoto T, Sakamoto S, Kasahara M, Saitoh A.
    • Journal Title

      J Clin Virol.

      Volume: 59(2) Issue: 2 Pages: 132-134

    • DOI

      10.1016/j.jcv.2013.11.015

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Simple and cost-effective restriction endonuclease analysis of human adenoviruses.2014

    • Author(s)
      Adhikary AK, Hanaoka N, Fujimoto T.
    • Journal Title

      Biomed Res Int.

      Volume: 363790 Pages: 1-6

    • DOI

      10.1155/2014/363790

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A case of atypical hand-foot-and-mouth disease caused by coxsackievirus A6: differential diagnosis from varicella in a pediatric intensive care unit.2013

    • Author(s)
      Yasui Y, Makino T, Hanaoka N, Owa K, Horikoshi A, Tanaka A, Suehiro Y, Shimizu H, Kanou K, Kobayashi M, Konagaya M, Fujimoto T.
    • Journal Title

      Jpn J Infect Dis.

      Volume: 66 Pages: 564-6

    • NAID

      130003390346

    • Related Report
      2013 Research-status Report
  • [Journal Article] Complete genomic DNA sequence of the East Asian spotted fever disease agent Rickettsia japonica2013

    • Author(s)
      2. Matsutani M, Ogawa M, Takaoka N, Hanaoka N, Toh H, Yamashita A, Oshima K, Hirakawa H, Kuhara S, Suzuki H, Hattori M, Kishimoto T, Ando S, Azuma Y, Shirai M.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 9 Pages: e71861-e71861

    • DOI

      10.1371/journal.pone.0071861

    • NAID

      120005367886

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical manifestations of coxsackievirus A6 infection associated with a major outbreak of hand, foot, and mouth disease in Japan.2013

    • Author(s)
      Kobayashi M, Makino T, Hanaoka N, Shimizu H, Enomoto M, Okabe N, Kanou K, Konagaya M, Oishi K, Fujimoto T.
    • Journal Title

      Jpn J Infect Dis.

      Volume: 66 Pages: 260-1

    • NAID

      130003381685

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 尿道炎におけるアデノウイルス について2014

    • Author(s)
      花岡希、伊藤晋、高梨真樹、安田満、出口隆、山岸拓也、藤本嗣人
    • Organizer
      第27回 日本性感染症学会学術大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2014-12-06 – 2014-12-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] マイコプラズマ、アデノウイルス、単純ヘルペス、膣トリコモナス」を含む尿道炎原因微生物の検討2014

    • Author(s)
      伊藤晋、安田満、高梨真樹、伊藤貴子、花岡希、前田真一、出口隆
    • Organizer
      第27回 日本性感染症学会学術大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2014-12-06 – 2014-12-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] インターネットを利用した感染症啓発における要点と課題2014

    • Author(s)
      花岡希
    • Organizer
      第87回 日本細菌学会総会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2013 Research-status Report
  • [Remarks] アデノウイルス解説ページ

    • URL

      http://www.nih.go.jp/niid/ja/adeno-pfc-m/2110-idsc/4th/4325-adeno-virus-page.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] リケッチア症啓発ページ

    • URL

      http://www0.nih.go.jp/niid/Rickettsia/

    • Related Report
      2014 Annual Research Report
  • [Remarks] アデノウイルス解説ページ

    • URL

      http://www.nih.go.jp/niid/ja/adeno-pfc-m/2110-idsc/4th/4325-adeno-virus-page.html

    • Related Report
      2013 Research-status Report
  • [Remarks] リケッチア症啓発ページ

    • URL

      http://www0.nih.go.jp/niid/Rickettsia/

    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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