| Project/Area Number |
25861465
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Akita University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 早産リスク / エラストグラム / 切迫早産 / 子宮頸管 |
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| Outline of Final Research Achievements |
We assessed the value of cervical tissue strain (TS) measured with elastography in comparison with the transvaginal cervical length (CL) and Bishop’s score (BS) for the prediction of the onset of spontaneous labor at term. Transvaginal cervical elastography may be a useful tool for predicting the onset of spontaneous labor in 10 days. With fewer days between examination and labor onset, CL and BS tended to be more sensitive predictors than TS. Using a total of 520 data gained by elastography, we compared cervical TS between women who were hospitalized by threatened preterm labor and women with no symptom of labor. The optimal cutoff value of cervical TS for predicting the onset of threatened preterm labor was 1.5, the odds ratio is 2.48 (95% CI: 1.28-4.79).
We made the new device which can measure stiffness of cervix directly. The intra- and inter-assay coefficients of a total of 100 examinations using this device were 0.650 and 0.641, respectively.
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