genetic susceptibility to endometriosis

• Project/Area Number: 25861477
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Obstetrics and gynecology
• Research Institution: Niigata University
• Principal Investigator: ADACHI SOSUKE 新潟大学, 医歯学総合病院, 助教 (50613147)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 子宮内膜症 / 全ゲノム関連解析 / SNP / 疾患感受性遺伝子

Outline of Final Research Achievements

We conducted an association study of 537 endometriosis cases and 528 controls of Japanese people. We confirmed that 3 SNPs that were previously reported to associate with endometriosis in genome-wide association study were associated with endometriosis in this replication study.