• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

C/EBP alpha is promotes the pathogenesis of endometriosis.

Research Project

Project/Area Number 25861500
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionOita University

Principal Investigator

KAWANO YUKIE  大分大学, 医学部, 講師 (60516128)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords子宮内膜症 / エピジェネティクス
Outline of Final Research Achievements

Accumulating evidence suggests that various epigenetic aberrations play definite roles in the pathogenesis of endometriosis. Our findings suggest that an epigenetically suppressed tumor suppressor gene is involved in the pathogenesis of endometriosis by creating the proliferative, antiapoptotic,and
other disease-specific characteristics of endometriosis. The results also suggest that histone deacetylase inhibitors are promising agents for the treatment of endometriosis.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] CCAAT/enhancer-binding protein  is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis.2013

    • Author(s)
      Kawano Y, Nasu K, Hijiya N, Tsukamoto Y, Amada K, Abe W, Kai K, Moriyama M, Narahara H
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 98 Issue: 9 Pages: E1474-E1482

    • DOI

      10.1210/jc.2013-1608

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 子宮内膜症病態形成におけるがん抑制遺伝子C/EBPαの関与についての検討2013

    • Author(s)
      川野 由紀枝
    • Organizer
      日本産科婦人科学会学術集会
    • Place of Presentation
      ロイトン札幌、ホテルさっぽろ芸文館、札幌プリンスホテル、札幌市教育文化会館
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi