The processing of dichotic listening in the mouse auditory cortex using flavoprotein fluorescence imaging
Project/Area Number |
25861536
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
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Research Institution | Niigata University |
Principal Investigator |
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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Keywords | 大脳聴覚野 / イメージング / マウス / 両耳分離補聴 / 聴覚リハビリ / 聴覚野 / フラビン蛋白蛍光イメージング / 視覚・聴覚連想記憶 / 分離補聴 / 周波数分解能 / フラビン蛋白 |
Outline of Final Research Achievements |
In patients with sensorineural hearing loss "I hear sound but I do not understand the words", we feel the limit of traditional hearing aid treatment. We focused on the possibility of dichotic listening system for improving speech intelligibility and a new auditory rehabilitation that associates shape and sound, ie visual and auditory sense. Mouse cerebral auditory cortex responses were observed using flavoprotein autofluorescence imaging. Data collection of dichotic listening was technically difficult. After the mouse was exposed by associating visual and auditory stimuli, cerebral auditory cortex responses were found only by looking at the shape without sound. I think that these results can contribute to further new auditory rehabilitation using sensory stimulation other than hearing.
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Report
(5 results)
Research Products
(5 results)
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[Presentation] The cortical area located dorsally to auditory cortex involved in sound-shape association memory in mice2015
Author(s)
Tatsuya Yamagishi , Hiroaki Tsukano , Hironori Baba, Yuusuke Honma , Shinsuke Ohshima, Yamato Kubota, Kuniyuki Takahashi, Ryuichi Hishida, Takeshi Yagi, Katsuei Shibuki , Sugata Takahashi
Organizer
The 30th Politzer Society Meeting
Place of Presentation
朱鷺メッセ(新潟県新潟市)
Year and Date
2015-06-30
Related Report
Int'l Joint Research
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[Presentation] Cortical depression in the mouse auditory cortex after sound discrimination learning
Author(s)
Shinsuke Ohshima, Kuniyuki Takahashi, Tatsuya Yamagishi, Hironori Baba, Yuusuke Honma, Hiroaki Tsukano, Yamato Kubota, Ryuichi Hishida, Katsuei Shibuki, Sugata Takahashi
Organizer
29th politzer society meeting
Place of Presentation
Antalya, Turkey
Related Report