| Project/Area Number |
25861553
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Department of Clinical Research, National Hospital Organization Kyoto Medical Center |
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Principal Investigator |
KADA Shinpei 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究員 (70543263)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 喉頭 / 声門下粘膜 / 質量顕微鏡 / コラーゲン / エラスチン / 脂質 / 声帯粘膜下組織 |
|---|
| Outline of Final Research Achievements |
Using mass microscope , we measured the lipid distribution of the human larynx . Previous studies revealed few constituents of such collagen and elastin in the submucosal tissue of the vocal cord. Now we revealed that the submucosal substance represents m / z 583.0 , m / z 605.0, and m / z 621.1 in the spectrum .
The substance identified by further mass microscope or these materials is what was done , it is not possible to obtain sufficient spectrum , until material identified did not reach . The cause is considered possible that the presence of the constituent materials is too small, in addition to the inadequate experimental conditions . In the future, only those portions make an integrated , we aim to elucidate the mass analysis .
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