Effective Embryoid Body Formation From Mouse Induced Pluripotent Stem Cells for Regeneration of Respiratory Epithelium
Project/Area Number |
25861576
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
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Research Institution | Fukushima Medical University |
Principal Investigator |
OTSUKI Koshi 福島県立医科大学, 医学部, 助教 (80633776)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | iPS細胞 / 気管上皮 / 胚様体 / 再生 |
Outline of Final Research Achievements |
The purpose of this study is to establish a technique to differentiate to respiratory epithelial tissue from induced pluripotent stem(iPS) cells, and to induce to reproduce tracheal tissue. Especially, current study determined the most effective conditions for embryoid body (EB) formation from iPS cells for regeneration of respiratory epitheium. This is the first study to demonstrate the potential of iPS cells for the regeneration of the respiratory epithelium.
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Report
(3 results)
Research Products
(4 results)