Effective Embryoid Body Formation From Mouse Induced Pluripotent Stem Cells for Regeneration of Respiratory Epithelium

Research Project

Project/Area Number	25861576
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Otorhinolaryngology
Research Institution	Fukushima Medical University
Principal Investigator	OTSUKI Koshi 福島県立医科大学, 医学部, 助教 (80633776)
Project Period (FY)	2013-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000) Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords	iPS細胞 / 気管上皮 / 胚様体 / 再生
Outline of Final Research Achievements	The purpose of this study is to establish a technique to differentiate to respiratory epithelial tissue from induced pluripotent stem(iPS) cells, and to induce to reproduce tracheal tissue. Especially, current study determined the most effective conditions for embryoid body (EB) formation from iPS cells for regeneration of respiratory epitheium. This is the first study to demonstrate the potential of iPS cells for the regeneration of the respiratory epithelium.

Report

(3 results)