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Effect of the electrical stimulation of the larynx on the medullary swallowing networks

Research Project

Project/Area Number 25861581
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

SUGIYAMA Yoichiro  京都府立医科大学, 医学部附属病院, 専攻医 (50629566)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords喉頭 / 嚥下 / 喉頭科学 / 神経生理学
Outline of Final Research Achievements

The swallowing center which provides sequential pharyngeal and laryngeal movements is located mainly in the medulla oblongata, and overlapped with the medullary respiratory neuronal networks. To evaluate whether the medullary respiratory neurons contribute to regulating swallowing behavior and thus play a critical role in the network plasticity due to the electrical stimulation of the larynx, we investigated activity and distribution of the respiratory-related neurons in the ventrolateral medulla during swallowing. Various types of respiratory neurons were recorded in this region and changed their activity during swallowing in a type specific manner, suggesting that the medullary swallowing networks can share the respiratory neuronal networks in the medulla oblongata.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Activity of respiratory neurons in the rostral medulla during vocalization, swallowing, and coughing in guinea pigs2014

    • Author(s)
      Sugiyama Y, Shiba K, Mukudai S, Umezaki T, Hisa Y
    • Journal Title

      Neurosci Res

      Volume: 80 Pages: 17-31

    • DOI

      10.1016/j.neures.2013.12.004

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed
  • [Presentation] モルモットにおける脳幹発声時の延髄呼吸ニューロン群の活動様式2014

    • Author(s)
      杉山庸一郎
    • Organizer
      第26回日本喉頭科学会
    • Place of Presentation
      沖縄県
    • Related Report
      2013 Research-status Report
  • [Presentation] モルモット延髄呼吸中枢における嚥下、咳活動制御様式2014

    • Author(s)
      杉山庸一郎
    • Organizer
      第37回日本嚥下医学会
    • Place of Presentation
      東京都
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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