Project/Area Number |
25861586
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
|
Research Institution | Jikei University School of Medicine |
Principal Investigator |
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 好酸球性副鼻腔炎 / 内視鏡下鼻内手術 / 一酸化窒素 / 慢性副鼻腔炎 / 好酸球 |
Outline of Final Research Achievements |
Eosinophilic chronic rhinosinusitis has a tendency of recurrence after the surgery. We classified the patients who had the surgery as good prognosis group, steroid effectiveness group, and steroid resistance group. In steroid resistance group, mucosal eosinophil count and IL-5 mRNA tended to higher, but significantly difference. In addition, the measurement of nasal FeNO may be an effective tool that assess the sinus mucosa condition during postoperative period.
|