Analysis of spatial distribution of synapses and morphology of the retinal ganglion cells.
| Project/Area Number |
25861612
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Tohoku University |
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Principal Investigator |
MORITOH Satoru 東北大学, 医学(系)研究科(研究院), 助手 (20647234)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 網膜神経節細胞 / 遺伝子銃 / 網膜培養 / シナプス / 緑内障 |
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| Outline of Final Research Achievements |
I developed organotypic tissue culture of porcine retina with particle-mediated gene transfer. Using this method, I successfully transfected cell morphological marker plasmid and synaptic marker plasmid into the porcine retinal ganglion cells. I examined morphology and synaptic position of the porcine retinal ganglion cells. I found several types of bistratified retinal ganglion cells including a candidate for direction-selective ganglion cells in porcine retinas.
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Report
(3 results)
Research Products
(1 results)
