Distinction of the factor with which a medicine search for improvement of results and a filtration vesica are concerned insufficiently after a glaucoma operation
| Project/Area Number |
25861613
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Tohoku University |
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Principal Investigator |
WATANABE Ryo 東北大学, 医学(系)研究科(研究院), 非常勤講師 (70625293)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 緑内障 / 線維柱帯切除術 / MIP1-β / サイトカイン / テノン嚢 / 前房水 / 線維柱帯切除 / 線維芽細胞増殖抑制 / 薬剤スクリーニング |
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| Outline of Final Research Achievements |
Medicine mitomycin C which is used for the time of fiber pillar area resection which passes to glaucoma has epithelia anterius corneae toxicity. When I did medicine search of a TENON vesica fiber sprout cell growth using the existence medicine library restrained in peculiar way, a hit compound was found 10 pills.
The previous aqueous humor was extracted at the time of a glaucoma operation, and correlation with the filtering method function of 6 months and the filtering method structure was considered after an operation with 27 kinds of site Cain density using Bio - Plex. MIP1-β admitted significant correlation in the ocular pressure and the filtration vesica structure after an operation.
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Report
(3 results)
Research Products
(7 results)
