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Distinction of the factor with which a medicine search for improvement of results and a filtration vesica are concerned insufficiently after a glaucoma operation

Research Project

Project/Area Number 25861613
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionTohoku University

Principal Investigator

WATANABE Ryo  東北大学, 医学(系)研究科(研究院), 非常勤講師 (70625293)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords緑内障 / 線維柱帯切除術 / MIP1-β / サイトカイン / テノン嚢 / 前房水 / 線維柱帯切除 / 線維芽細胞増殖抑制 / 薬剤スクリーニング
Outline of Final Research Achievements

Medicine mitomycin C which is used for the time of fiber pillar area resection which passes to glaucoma has epithelia anterius corneae toxicity. When I did medicine search of a TENON vesica fiber sprout cell growth using the existence medicine library restrained in peculiar way, a hit compound was found 10 pills.
The previous aqueous humor was extracted at the time of a glaucoma operation, and correlation with the filtering method function of 6 months and the filtering method structure was considered after an operation with 27 kinds of site Cain density using Bio - Plex. MIP1-β admitted significant correlation in the ocular pressure and the filtration vesica structure after an operation.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (7 results)

All 2013

All Journal Article (1 results) Presentation (6 results)

  • [Journal Article] Retina施設めぐり【外来施設編】東北大学病院眼科2013

    • Author(s)
      渡邉 亮、横倉 俊二、中澤 徹
    • Journal Title

      Retina Medicine

      Volume: Vol.2 No.2 Pages: 94-95

    • Related Report
      2013 Research-status Report
  • [Presentation] 後期緑内障患者者における視野進行評価法2013

    • Author(s)
      渡邉 亮、国松 志保、横山 悠、今野 瑛之、劉 孟林、高橋 秀肇、中澤 徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 前眼部3次元OCTを用いた線維柱帯切除術後の濾過胞の評価2013

    • Author(s)
      國分 太貴、津田 聡、浅野 俊文、横山 悠、面高 宗子、多田 麻子、渡邉 亮、劉 孟林、国松 志保、高橋 秀肇、丸山 和一、中澤 徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 線維柱帯切除後の濾過胞における経時的結膜炎血管面積の低量化2013

    • Author(s)
      浅野 俊文、津田 聡、國分 太貴、横山 悠、面高 宗子、渡邉 亮、劉 孟林、国松 志保、高橋 秀肇、丸山 和一、中澤 徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 東北大学病院における毛様体光凝固術の術後成績2013

    • Author(s)
      多田 麻子、国松 志保、丸山 和一、高橋 秀肇、劉 孟林、渡邉 亮、檜森 紀子、横山 悠、津田 聡、志賀 由己浩、中澤 徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] Correlation of cytokines in the aqueous humor and functional prognosis of the bleb after trabeculectomy 濾過胞の生存に関与する前房水サイトカインの検討2013

    • Author(s)
      國分 太貴、津田 聡、安田 正幸、清水 愛、横山 悠、渡邉 亮、劉 孟林、国松 志保、丸山 和一、中澤 徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 繊維柱帯切除後の濾過胞における経時的結膜血管面積の定量化2013

    • Author(s)
      浅野 俊文、津田 聡、國分 太貴、横山 悠、面高 宗子、渡邉 亮、劉 孟林、国松 志保、高橋 秀肇、丸山 和一、中澤 徹
    • Organizer
      第67回日本臨床眼科学会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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