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Investigation of visual field employing Bayes and machine learning method

Research Project

Project/Area Number 25861618
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionThe University of Tokyo

Principal Investigator

MURATA Hiroshi  東京大学, 医学部附属病院, 助教 (80635748)

Co-Investigator(Renkei-kenkyūsha) ASAOKA Ryo  東京大学, 医学部附属病院眼科, 臨床講師 (00362202)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords緑内障 / 視野 / ベイズ統計 / 変分ベイズ / 平均場近似 / ベイズ線形回帰 / ゲイズトラック / 機械学習
Outline of Final Research Achievements

Glaucoma is characterized by progressive visual field (VF) damage, which is irreversible, so it is important to predict VF progression in clinical use. In Humphrey Field Analyzer (HFA), which is commonly used in clinical settings, employs simple linear regression for analysis of VF data. However, it ignores the correlation between test points and so on.
We created a novel model for VF progression, and by means of learning the model using a lot of data we had, we were able to predict future VF more precisely than simple linear regression.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2015 2014 2013

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 3 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] Do pattern deviation values accurately estimate glaucomatous visual field damage in eyes with glaucoma and cataract?2015

    • Author(s)
      A. Matsuda, T. Hara, K. Miyata, H. Matsuo, H. Murata, C. Mayama and R. Asaoka
    • Journal Title

      The British journal of ophthalmology

      Volume: 99 Issue: 9 Pages: 1240-1244

    • DOI

      10.1136/bjophthalmol-2014-306019

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Applying 'Lasso' regression to predict future visual field progression in glaucoma2015

    • Author(s)
      Y. Fujino, H. Murata, C. Mayama and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 56 Issue: 4 Pages: 2334-9

    • DOI

      10.1167/iovs.15-16445

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Targeting a Low-Teen Intraocular Pressure by Trabeculectomy With a Fornix-based Conjunctival Flap: Continuous Japanese Case Series by a Single Surgeon2015

    • Author(s)
      Y. Aoyama, H. Murata and M. Aihara
    • Journal Title

      Journal of glaucoma

      Volume: 24 Issue: 3 Pages: 225-232

    • DOI

      10.1097/ijg.0000000000000219

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An objective evaluation of gaze tracking in Humphrey perimetry and the relation with the reproducibility of visual fields: a pilot study in glaucoma2014

    • Author(s)
      Y. Ishiyama, H. Murata, C. Mayama and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 55 Issue: 12 Pages: 8149-52

    • DOI

      10.1167/iovs.14-15541

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A new approach to measure visual field progression in glaucoma patients using variational bayes linear regression2014

    • Author(s)
      H. Murata, M. Araie and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 12 Issue: 12 Pages: 8386-8392

    • DOI

      10.1167/iovs.14-14625

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A Method to Measure Visual Field Sensitivity at the edges of Glaucomatous Scotomata.2014

    • Author(s)
      Aoyama Y, Murata H, Tahara M, Yanagisawa M, Hirasawa K, Mayama C, Asaoka R.
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: in press Issue: 4 Pages: 2584-91

    • DOI

      10.1167/iovs.13-13616

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Combining multiple HRT parameters using the 'Random Forests' method improves the diagnostic accuracy of glaucoma, in emmetropic and highly myopic eyes2014

    • Author(s)
      Asaoka R, Iwase A, Tsutsumi T, Saito H, Otani S, Miyata K, Murata H, Mayama C, Araie M.
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: in press Issue: 4 Pages: 2482-2482

    • DOI

      10.1167/iovs.14-14009

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Impact of better and worse eye damage on quality of life in advanced glaucoma2014

    • Author(s)
      Okamoto M, Sugisaki K, Murata H, Hirasawa H, Mayama C, Asaoka R.
    • Journal Title

      Scientific reports

      Volume: 4 Issue: 1 Pages: 4144-4144

    • DOI

      10.1038/srep04144

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cross-sectional study: Does combining optical coherence tomography measurements using the 'Random Forest' decision tree classifier improve the prediction of the presence of perimetric deterioration in glaucoma suspects?2013

    • Author(s)
      Sugimoto K, Murata H, Hirasawa H, Aihara M, Mayama C, Asaoka R.
    • Journal Title

      BMJ open

      Volume: 3 Issue: 10 Pages: e003114-e003114

    • DOI

      10.1136/bmjopen-2013-003114

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Intraocular pressure change over a habitual 24-hour period after changing posture or drinking water and related factors in normal tension glaucoma.2013

    • Author(s)
      Sakata R, Aihara M, Murata H, Saito H, Iwase A, Yasuda N, Araie M.
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 54 Issue: 8 Pages: 5913-20

    • DOI

      10.1167/iovs.13-11792

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Detection of progression of glaucomatous visual field damage using the point-wise method with the binomial test2013

    • Author(s)
      Karakawa A, Murata H, Hirasawa H, Mayama C, Asaoka R.
    • Journal Title

      PloS one

      Volume: 8 Issue: 10 Pages: e78630-e78630

    • DOI

      10.1371/journal.pone.0078630

    • Related Report
      2013 Research-status Report
    • Peer Reviewed

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Published: 2014-07-25   Modified: 2019-07-29  

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