| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
In Fuchs endothelial corneal dystrophy, the corneal is damaged more severely in the center and paracentral zones than in the peripheral, and peripheral measurement can objectively grade the disease. In the peripheral zones, the inferotemporal endothelium is damaged. Chronologic measurements of in keratoconus demonstrated that the progression of steepening at posterior corneal surface was found not only in patients under 30 years but also in older patients. The rate of progression is predicted by mapping of corneal curvature and thickness, and the risk of progression was greater in younger patients with steeper maximal K value.
Exclusively in the song nucleiin zebra finch, an increase in expression of high-sulfated keratan sulfate (KS) started after hatching, and reached a plateau at the end of the sensory period. Ubiquitous expression of low-sulfated KS remained unchanged until the end of the sensory period, and first increased in the song nuclei at the end of the sensorimotor period.
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