Identification of genes associated with the development of organ lesions in sarcoidosis
Project/Area Number |
25861643
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Ophthalmology
|
Research Institution | Yokohama City University |
Principal Investigator |
|
Research Collaborator |
MIZUKI Nobuhisa
MEGURO Akira
SATO Mayuki
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | サルコイドーシス / 遺伝子 |
Outline of Final Research Achievements |
Sarcoidosis is a chronic systemic disease characterized by the accumulation of non-caseating granulomas in a wide range of organs such as lungs, lymph nodes, eye, skin and heart. The etiology of sarcoidosis is still uncertain, but the disease is currently thought to be triggered by various genetic as well as environmental factors. In this study, we investigated genetic factors associated with each organ legion in sarcoidosis using a genome-wide association study data in a Japanese population and identified several genes that may contribute to the development of each organ legion.
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Report
(3 results)
Research Products
(6 results)
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[Journal Article] Development and validation of new diagnostic criteria for acute retinal necrosis.2015
Author(s)
Takase H, Okada AA, Goto H, Mizuki N, Namba K, Ohguro N, Sonoda KH, Tomita M, Keino H, Kezuka T, Kubono R, Mizuuchi K, Shibuya E, Takahashi H, Yanai R, Mochizuki M
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Journal Title
Jpn J Ophthalmol
Volume: 59(1)
Issue: 1
Pages: 14-20
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Evaluation of the long-term efficacy and safety of infliximab treatment for uveitis in Behçet's disease: a multicenter study.2014
Author(s)
Takeuchi M, Kezuka T, Sugita S, Keino H, Namba K, Kaburaki T, Maruyama K, Nakai K, Hijioka K, Shibuya E, Komae K, Hori J, Ohguro N, Sonoda KH, Mizuki N, Okada AA, Ishibashi T, Goto H, Mochizuki M
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Journal Title
Ophthalmology
Volume: 121(10)
Issue: 10
Pages: 1877-1884
DOI
Related Report
Peer Reviewed / Open Access
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