| Project/Area Number |
25861678
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 脳血流 / インドシアニングリーン色素 / マイクロサージェリー / 脳血流評価 / 脳皮質血流 / 血管吻合 |
|---|
| Outline of Final Research Achievements |
Decrease in cerebral blood flow was reported in depressed individuals. We aimed at making an animal model of this using rats. We succeeded in visualization of small cerebral vessels on the surface of rat brain by infusing ICG. By taking a short video, we were able to analyze the actual blood flow. In addition, my using a device emitting a special light that is absorbed only by hemoglobin, we were able to visualize vessels as small as 0.2 mm. This was tested in human veins of the fingertips. By analyzing the time difference of its brightness, we could evaluate the amount of blood flow.
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