| Project/Area Number |
25861705
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Keio University |
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Principal Investigator |
TAKADA Keiko 慶應義塾大学, 医学部, 助教 (80624460)
|
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| Research Collaborator |
ARAMAKI Noriko 慶應義塾大学, 形成外科, 講師 (80365311)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 細胞外マトリックス / 毛 / versican / 毛乳頭 / ADAMTS |
|---|
| Outline of Final Research Achievements |
Versikine was detected in anagen of dermal papilla, but not in catagen by immunohistochemistry. Adamts-1,4,5 were shown in dermal papilla cells by RT-PCR.
Versikine was produced in dermal papilla from cleavage of versican by ADAMTSs.
From our data, versikine has an effect to promote dermal papilla cells and play an important role in hair cycles.
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