| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The sections of costal cartilage was harvested from 10-week-old wild rats and transplanted to dorsal region of 10-week-old green fluorescent protein (GFP) transgenic rat. These were subcutaneously harvested from GFP rats at 4-weekes and 8- weeks. This experiment was carried out in 2 randomized groups, with the perichondrium removed from the transplanted cartilage in one group, and with intact perichondrium transplanted. The GFP-positive chondrocytes in 8 weeks later in the group of the perichondrium removed. The GFP-positive chondrocytes was not replaced in the group of perichondrium intact. This result showed cartilage was reproduced from membrane-like tissue regenerated around cartilage after removing the perichondrium; continuously generating new chondrocytes.
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