| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
We investigated the influence of mechanical stress on the temporomandibular joint (TMJ) in a rabbit model. We divided the rabbits into 2 groups, traction and compressive, and compared them at each period.Tractional mechanical stress led to changes in the form of the condyle, including significantly reduced bone volume and decreased bone mineral density. In addition, the number of TRAP-positive cells was increased in the traction group during each period. Furthermore, subchondral bone formation disorders were more prominent in the traction group as compared to the compressive group.Our findings demonstrated that the TMJ may be more affected by tractional than compressive mechanical stress.Moreover, we speculate that condylar resorption is related to subchondral cells, though findings following immunohistochemical staining are needed as part of a future examination.
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