Project/Area Number |
25861782
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Pathobiological dentistry/Dental radiology
|
Research Institution | Asahi University |
Principal Investigator |
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 口腔細菌 / 宿主応答 / Porphyromonas gingivalis / 抗菌性因子 |
Outline of Final Research Achievements |
Antimicrobial factors produced from the salivary glands play an important role in maintaining homeostasis of the oral cavity. However, on the other hand, the mechanism of production of antimicrobial factors by salivary glands is not currently understood. Although salivary glands despite not subject to direct exposure of oral bacteria, what mechanisms is involved in production of antibacterial factors. In this study, the effects of oral bacteria on production of antibacterial factors by the salivary glands are investigated.
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