| Project/Area Number |
25861792
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Conservative dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TAKAHASHI Rena 東京医科歯科大学, 歯学部附属病院, 助教 (40613609)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 象牙質透過性 / 脱灰 / ハイドロキシアパタイト |
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| Outline of Final Research Achievements |
This study evaluated the permeability of dentin with/without resin coating in different storage media and period. Prepared bovine dentin disks were divided into three groups: 1) left uncoated as a control, 2) resin-coated with Clearfil SE Bond (SE) only and 3) coated with the combination of SE and Clearfil Protect Liner F (SE+PLF). The hydraulic conductance (Lp) of each specimen was measured after storage in either deionized water or artificial saliva. The Lp value was expressed as the percentage of baseline hydraulic conductance (Lp%). For the control group, the mean Lp% after 1, 30 and 90 days were 103.7%, 126.0% and 128.6% in deionized water and 92.5%, 64.4% and 62.2% in artificial saliva, respectively. The Lp% of SE+PLF after 1 day in artificial saliva yielded the lowest Lp% (2.5%) among all the groups. Application of the resin coating to dentin surface demonstrated remarkable reduction of dentin permeability over time.
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