Development of self-reinforced adhesive system

• Project/Area Number: 25861792
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: TAKAHASHI Rena 東京医科歯科大学, 歯学部附属病院, 助教 (40613609)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 象牙質透過性 / 脱灰 / ハイドロキシアパタイト

Outline of Final Research Achievements

This study evaluated the permeability of dentin with/without resin coating in different storage media and period. Prepared bovine dentin disks were divided into three groups: 1) left uncoated as a control, 2) resin-coated with Clearfil SE Bond (SE) only and 3) coated with the combination of SE and Clearfil Protect Liner F (SE+PLF). The hydraulic conductance (Lp) of each specimen was measured after storage in either deionized water or artificial saliva. The Lp value was expressed as the percentage of baseline hydraulic conductance (Lp%). For the control group, the mean Lp% after 1, 30 and 90 days were 103.7%, 126.0% and 128.6% in deionized water and 92.5%, 64.4% and 62.2% in artificial saliva, respectively. The Lp% of SE+PLF after 1 day in artificial saliva yielded the lowest Lp% (2.5%) among all the groups. Application of the resin coating to dentin surface demonstrated remarkable reduction of dentin permeability over time.

Research Products

• [Journal Article] The effect of curing conditions on the dentin bond strength of two dual-cure resin cements (2017)
  • Author(s): Atsuko Tagami, Rena Takahashi, Toru Nikaido, Junji Tagami
  • Journal Title: Journal of Prosthodontic Research Volume: 61 Issue: 4 Pages: 412-418
  • DOI: 10.1016/j.jpor.2016.12.012
  • NAID: 130006198540
  • ISSN: 1883-1958, 1883-9207
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Root caries management: Evidence and consensus based report (2016)
  • Author(s): Yasuko Momoi, Akihiko Shimizu, Mikako Hayashi, Satoshi Imazato, Masako Unemori, Yuichi Kitasako, Shisei Kubo, Rena Takahashi, Syozi Nakashima, Toru Nikaido, Masayoshi Fukushima, Morioki Fujitani, Chinami Yamaki, Kenichi Sugai
  • Journal Title: Cariology in Current Oral Health Reports Volume: 3 Issue: 2 Pages: 117-123
  • DOI: 10.1007/s40496-016-0084-0
  • Peer Reviewed / Open Access
• [Journal Article] Resin Coating Technique for Protection of Pulp and Increasing Bonding in Indirect Restoration (2015)
  • Author(s): Toru Nikaido, Go Inoue, Tomohiro Takagaki, Rena Takahashi, Alireza Sadr, Junji Tagami.
  • Journal Title: Current Oral Health Reports Volume: 2 Issue: 2 Pages: 81-86
  • DOI: 10.1007/s40496-015-0046-y
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Change of dentin permeability in different storage media after resin coating (2015)
  • Author(s): Hua Qiao, Rena Takahashi, Toru Nikaido, Syozi Nakashima, Alireza Sadr, Masaomi Ikeda, Junji Tagami
  • Journal Title: Asian Pacific Journal of Dentistry Volume: 2 Pages: 33-40
  • NAID: 40020713139
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Surface properties of universal and flowable nanohybrid composites after simulated tooth brushing. (2014)
  • Author(s): Jin Jin, Takahashi Rena, Hickel Reinhard, Kunzelmann Karl-Heintz
  • Journal Title: American Journal of Dentistry Volume: 27 Pages: 149-154
  • Peer Reviewed
• [Journal Article] Surface characterization of current composites after toothbrush abrasion. (2013)
  • Author(s): Rena Takahashi, Jian Jin, Toru Nikaido, Junji Tagami, Reinhard Hickel, Karl-Heinz Kunzelmann
  • Journal Title: Dental Materials Journal Volume: 32 Pages: 75-82
  • NAID: 10031138704
  • Peer Reviewed
• [Presentation] Comparison of light-cured pit and fissure sealants on enamel demineralization using swept-source optical coherence tomography (2016)
  • Author(s): Rena Takahashi, Yasushi Shimada, Yu-Chih Chiang, Ikumi Wada, Yasunori Sumi, Junji Tagami
  • Organizer: 94th General Session & Exhibition of the IADR
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-06-24
  • Int'l Joint Research
• [Presentation] Bonding Property of Resin Cement to Composite Resin Crown (2015)
  • Author(s): Oto Aramaki, Rena Takahashi , Takahiro Wada, Motohiro Uo, Junji Tagami
  • Organizer: Academy of Dental Materials
  • Place of Presentation: Maui (USA)
  • Year and Date: 2015-10-08
  • Int'l Joint Research
• [Presentation] Effect of curing mode and restoration thickness on tensile bond strength of a dual-cure resin cement to dentin (2015)
  • Author(s): Atsuko Tagami, Rena Takahashi, Toru Nikaido, Junji Tagami
  • Organizer: 7th TMDU International Summer Program (ISP2015)
  • Place of Presentation: 東京医科歯科大学（東京都文京区）
  • Year and Date: 2015-08-29
  • Int'l Joint Research