Study of occlusal disconfort with prosthetic treatment

• Project/Area Number: 25861831
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: SATO YUSUKE 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (10451957)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
• Keywords: 歯科補綴学 / 歯科心身症 / 咬合異常感 / 歯科補綴

Outline of Final Research Achievements

Most of Phantom Bite Syndrome patients had treated occlusion in dental hospital. They were strongly particular about their occlusion. Phantom Bite Syndrome is generally not associated with severe psychiatric disorders. Absence of a dental trigger predicts a psychiatric comorbidity, which affects the psychopharmacological outcome. Antidepressant or antipsychotic therapy may be effective for symptom management in Phantom Bite Syndrome. The visual assessment by SPECT revealed a right > left perfusion asymmetry in broad areas of the brain among the patients. We analyze Oral health related QOL of neurotic complete denture wearers by using SEM.

Research Products

• [Journal Article] Psychiatric comorbidities and psychopharmacological outcomes of phantom bite syndrome. (2015)
  • Author(s): Watanabe M, Umezaki Y, Suzuki S, Miura A, Shinohara Y, Yoshikawa T, Sakuma T, Shitano C, Katagiri A, Sato Y, Takenoshita M, Toyofuku A.
  • Journal Title: J Psychosom Res. Volume: 78 Issue: 3 Pages: 255-9
  • DOI: 10.1016/j.jpsychores.2014.11.010
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] アミトリプチリンにアリピプラゾールの追加が奏功した非定型歯痛の2例 (2014)
  • Author(s): 竹之下 美穂, 渡邉 素子, 鈴木 スピカ, 篠原 優貴子, 三浦 杏奈, 佐藤 佑介, 片桐 綾乃, 佐久間 朋美, 舌野 知佐, 吉川 達也, 豊福 明
  • Journal Title: 日本歯科心身医学会雑誌 Volume: 29(1) Pages: 34-38
  • Peer Reviewed
• [Journal Article] 舌痛症の抗うつ薬への反応性に関与する因子についての臨床的検討 (2014)
  • Author(s): 吉川 達也，渡邉 素子, 鈴木 スピカ, 篠原 優貴子, 三浦 杏奈, 舌野 知佐, 片桐 綾乃, 佐久間 朋美, 竹之下 美穂, 佐藤 佑介, 豊福 明
  • Journal Title: 日本歯科心身医学会雑誌 Volume: 29(1) Pages: 17-23
  • Peer Reviewed
• [Journal Article] Brain perfusion asymmetry in patients with oral somatic delusions (2013)
  • Author(s): Umezaki Y, Katagiri A, Watanabe M, Takenoshita M, Sakuma T, Sako E, Sato Y, Toriihara A, Uezato A, Shibuya H, Nishikawa T, Motomura H, Toyofuku A
  • Journal Title: Eur Arch Psychiatry Clin Neurosci Volume: VOL. 263, NO. 4 Issue: 4 Pages: 315-23
  • DOI: 10.1007/s00406-013-0390-7
  • Peer Reviewed
• [Journal Article] 症状の改善に伴い局所脳血流量の変化が見られたphantom bite syndromeの１例 (2013)
  • Author(s): 梅崎陽二郎，渡邉素子，竹之下美穂，吉川達也，佐久間朋美，酒向絵美，片桐綾乃，佐藤佑介，豊福明
  • Journal Title: 日本歯科心身医学会雑誌 Volume: 28 Pages: 30-34
  • Peer Reviewed
• [Presentation] 舌痛症の抗うつ薬治療における口腔乾燥感と唾液分泌量の経時的変化 (2014)
  • Author(s): 鈴木スピカ，渡邉素子，三浦杏奈，篠原優貴子，吉川達也，佐久間朋美，舌野知佐，片桐綾乃，梅崎陽二郎，佐藤佑介，竹之下美穂，豊福明
  • Organizer: 第２９回日本歯科心身医学会
  • Place of Presentation: 神奈川歯科大学横浜クリニック
  • Year and Date: 2014-07-26 – 2014-07-27
• [Presentation] 症状の改善に伴い局所血流量の変化が見られたphantom bite syndromeの１例 (2013)
  • Author(s): 梅崎陽二郎，渡邉素子，竹之下美穂，吉川達也，佐久間朋美，酒向絵美，片桐綾乃，佐藤佑介，豊福明
  • Organizer: ２８回日本歯科心身医学会
  • Place of Presentation: 福岡
• [Presentation] アリピプラゾールが奏効した非定型歯痛の２例 (2013)
  • Author(s): 竹之下美穂，梅崎陽二郎，渡邉素子，鈴木スピカ，片桐綾乃，佐藤佑介，酒向絵美，佐久間朋美，吉川達也，豊福明
  • Organizer: ２８回日本歯科心身医学会
  • Place of Presentation: 福岡