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Elucidation of factors which affects bone healing in teeth extraction sockets.

Research Project

Project/Area Number 25861837
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Research InstitutionNiigata University

Principal Investigator

MIKAMI Emi  新潟大学, 医歯学総合病院, 医員 (20419328)

Project Period (FY) 2014-02-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords抜歯窩治癒 / 歯槽骨生検 / マイクロCT / 骨リモデリング / 骨形態計測 / 微細骨梁構造 / ヒト / 歯槽骨リモデリング
Outline of Final Research Achievements

The purpose was to determine whether the bone remodeling in human tooth extraction sockets attained points of relative stability, and if so, at which post-extraction times such points would be reached. Subjects were 5 males and 31 females receiving implant operations or dental transplantation surgery. Post-extraction times ranged from 1.6 to 360 months. The alveolar bone biopsy samples were analyzed using micro-computed tomography and three-dimensional bone morphometry. Various alveolar bone parameters were plotted against post-extraction times, and a stepwise piecewise linear regression analysis was performed. The period between 7 and 12 months post-extraction was found to contain the greatest number of inflection points. Once these changes reached their respective inflection points, the time-related changes stopped. In the human alveolar bone, dynamic remodeling of the trabecular structure was found to continue to occur until the 7th - 12th month post-extraction.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (2 results)

All 2016 2015

All Presentation (2 results)

  • [Presentation] ヒト抜歯後歯槽堤における骨改造現象と骨代謝活性の抜歯後期間による違い -骨形態計測学的・組織学的解析-2016

    • Author(s)
      田中みか子,三上絵美,櫻井直樹,芳澤享子,荒井良明,山田一穂,江尻貞一,小野高裕
    • Organizer
      第46回公益社団法人日本口腔インプラント学会学術大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 抜歯窩歯槽骨の骨梁構造および骨塩量と抜歯後経過期間との関係.2015

    • Author(s)
      三上絵美,田中みか子,櫻井直樹,芳澤享子,荒井良明,山田一穂,江尻貞一,小野高裕
    • Organizer
      日本補綴歯科学会第124回学術大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県・さいたま市)
    • Year and Date
      2015-05-29
    • Related Report
      2015 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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