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Bio-active effect of inorganic polyphosphoric to achieve new innovation for bone quality

Research Project

Project/Area Number 25861845
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Research InstitutionHiroshima University

Principal Investigator

MORITA Koji  広島大学, 大学病院, 助教 (30555149)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsポリリン酸 / 骨再生 / 表面形状 / アパタイト
Outline of Final Research Achievements

This study was designed to elucidate the effect of HA plate adsorbed with PolyP-65 on proliferation or differentiation of MC3T3-E1 cells. After we confirmed adsorption of PolyP-65 onto the surface of HA plate, Surface roughness, water contact angle of HA plate adsorbed with PolyP-65, and calcium deposition and osteoblast differentiation in MC3T3-E1 culture were evaluated. Within the limited results of this study, it may be concluded that HA plate adsorbed with PolyP-65 at high concentration enhances calcification by binding calcium ion from medium, promoting differentiation of MC3T3-E1 cells.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2014

All Presentation (3 results)

  • [Presentation] ポリリン酸のハイドロキシアパタイトプレートに対する表面処理および骨芽細胞分化促進の評価2014

    • Author(s)
      森田晃司,土井一矢,岡崎洋平,久保隆靖,平田伊佐雄,加藤功一,津賀一弘
    • Organizer
      日本歯科理工学会第64回秋期学術講演会
    • Place of Presentation
      広島
    • Year and Date
      2014-10-04 – 2014-10-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] ポリリン酸はハイドロキシアパタイトプレート上で骨芽細胞様細胞の分化を促進する2014

    • Author(s)
      加藤寛,森田晃司,土井一矢,久保隆靖,津賀一弘
    • Organizer
      日本インプラント学会第44回学術大会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-12 – 2014-09-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 口腔検査の保険導入を目指した広島大学病院 口腔検査センターの取組み2014

    • Author(s)
      新谷智章、北川雅恵、吉岡幸男、土井充、荒川真、中元崇、小西有希子、應原一久、高明善 、西裕美、森田晃司、阿部倉仁、吉川峰加、久保隆靖、武知正晃、岡田貢、小川郁子、栗原英見
    • Organizer
      第7回日本口腔検査学会
    • Place of Presentation
      岡山市
    • Year and Date
      2014-09-05 – 2014-09-06
    • Related Report
      2014 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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