| Project/Area Number |
25861877
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Neuropsychiatric Research Institute |
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Principal Investigator |
FUKUDA Tatsuya 公益財団法人神経研究所, 研究部, 研究員 (90624833)
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| Research Collaborator |
TSUIKI Satoru
TAKEI Yoichiro
KOBAYASHI Mina
MINAMINO Osamu
SOGA Yusaku
ISONO Shiroh
INOUE Yuichi
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 閉塞性睡眠時無呼吸症候群 / 口腔内装置 / 舌位置 / 舌吸引 / 睡眠時無呼吸症候群 |
|---|
| Outline of Final Research Achievements |
During wakefulness, apneic events, even in patients with Obstructive Sleep Apnea (OSA), hardly occur regardless of the presence or absence of such episodes while asleep, because the augmented activity of the genioglossus muscle acts to patent the upper airway by maintaining the tongue in position. Hence, it is reasonable to hypothesize that OSA could be alleviated if the awake tongue position is maintained despite a sleep-related reduction in genioglossus muscle activity. It was found that continuous tongue suction to maintain the tongue in the awake position improved OSA. This approach represents a potential alternative for OSA treatment without application of positive airway pressure and mandibular/tongue advancement treatment.
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