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Investigation of neuroinflammation in human neuropathic pain with in vivo neuroimaging

Research Project

Project/Area Number 25861921
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionNiigata University

Principal Investigator

KURATA Shigenobu  新潟大学, 医歯学系, 助教 (20464018)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords下歯槽神経 / MRI / 三叉神経 / T2強調画像 / 神経炎症
Outline of Final Research Achievements

It was the purpose of this study to elucidate the presence of neuroinflammation in human neuropathic pain following inferior alveolar nerve injury. With a 1.5 tesla MRI device, we investigated development of the new high-resolution 3D volume rendering magnetic resonance neurography, visualization of inferior alveolar nerve with a surface coil and application of magnetic resonance angiography to inferior alveolar neurovascular bundle. Consequently, we were able to visualize inferior alveolar nerve well. Therefore, we thought to be in the process of establishing the basis of non-invasively investigating of the relationship for neuroinflammation and human neuropathic pain following inferior alveolar nerve injury. But, we need further investigation to the establishment.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (1 results)

All Other

All Presentation (1 results)

  • [Presentation] 3DVR-MRNを用いた外傷後の下歯槽神経に対する体積測定による病変解析

    • Author(s)
      倉田行伸、照光真、松澤等、田中裕、弦巻立、金丸博子、吉川博之、小玉由記、山崎麻衣子、佐藤由美子、瀬尾憲司
    • Organizer
      日本歯科麻酔学会
    • Place of Presentation
      新横浜国際ホテル(神奈川県横浜市)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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