The investigation of effects of occlusal stimuli on vascular dynamics in periodontium and incidence of root resorption

Research Project

Project/Area Number	25862015
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Orthodontics/Pediatric dentistry
Research Institution	Hiroshima University
Principal Investigator	MOTOKAWA MASAHIDE 広島大学, 大学病院, 病院助教 (90457268)
Research Collaborator	KIMURA Aya
Project Period (FY)	2013-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	歯科矯正学 / 咬合低機能
Outline of Final Research Achievements	This study revealed that root size and PDL structure may be reduced due to disuse atrophy resulting from a defect in occlusal function, but may be recovered following a gain of occlusal stimuli. It was also suggested that occlusal stimuli regulate PDL area through expression of VEGF and bFGF in rat PDL. Furthermore, the present study suggested that the application of the orthodontic force to hypofinctional tooth occur more severe root resorption than functional tooth. It was emphasized that root resorption may be prevented by its recovery of occusal function which stimulates the periodontal tissues.

Report

(3 results)