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Establishment of periodontal tissue regeneration therapy with intentional replantation using a growth factor and residual periodontal ligament

Research Project

Project/Area Number 25862053
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Periodontology
Research InstitutionKagoshima University

Principal Investigator

TAKEUCHI NAOSHI  鹿児島大学, 医歯(薬)学総合研究科, 客員研究員 (60630762)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords歯根膜 / 根分岐部病変 / 意図的再植 / エムドゲイン / 歯周組織再生療法 / アンキローシス / 歯根吸収 / 根分岐部病変3度
Outline of Final Research Achievements

The therapy for through-and-through furcation involvement in molar caused by severe chronic periodontitis has not yet been established. In this study, remaining healthy periodontal ligament induces bone regeneration for such a severe furcation involvement by re-planted interchanged mesiodistal root. Furthermore, thr effect of growth factor Enamel Matrix Derivative (Emdogain) for the purpose of suppressing Ankyrosis or root resorption was not observed. However, it is suggested that further effective and reliable bone regeneration could be expected by appropriate root distance or divergence of roots.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Effects of EMD in combination with bone swaging and calcium phosphate bone cement on periodontal regeneration in one-wall intrabony defects in dogs.2013

    • Author(s)
      Shirakata Y, Yoshimoto T, Takeuchi N, Taniyama K, Noguchi K.
    • Journal Title

      J Periodontal Res

      Volume: 48 Issue: 5 Pages: 37-43

    • DOI

      10.11607/prd.0989

    • Related Report
      2013 Research-status Report
    • Peer Reviewed

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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