| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
The purpose of this study was to clarify the association between periodontal disease and arteriosclerosis in a general rural Japanese population, taking into account the different pathological conditions indicated by the respective indices evaluated. The study cohort comprised 409 individuals at least 55 years of age residing in Ohasama, rural community in northern Japan. The probing pocket depth was significantly related to brachial-ankle pulse wave velocity (baPWV). On the other hand, the bone loss was significantly associated with augmentation index (AI). In a general rural Japanese population, periodontal disease was associated with arterial stiffness, and this association was found to have different characteristics depending on the properties of the indices evaluated. This result suggests that maintaining good oral hygiene through periodontal treatment is effective for preventing and mitigating different arteriosclerosis-related pathological conditions.
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