Changes in oxidative stress and anti-oxidative potency during delivery

Research Project

Project/Area Number	25862197
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Lifelong developmental nursing
Research Institution	Nagoya City University
Principal Investigator	Tanaka Izuka 名古屋市立大学, 看護学部, 助教 (70620805)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000) Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000) Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	酸化ストレス度 / 抗酸化力 / 妊婦 / 産婦 / 分娩 / 血液 / 酸化ストレス / 妊産婦 / 分娩第１期 / 分娩第３期
Outline of Final Research Achievements	The present study aimed to determine changes and factors involved in oxidative stress and anti-oxidative potency during delivery in post-partum women. Oxidative stress was higher and anti-oxidative stress was lower during delivery than during the third trimester. The amounts of oxidative stress during the third trimester correlated with that during and after delivery. Oxidative stress during delivery correlated with the body mass index (BMI) of non-pregnant women. These results showed that while delivery correlates with high levels of oxidative stress, weight control during pregnancy is important for maintaining low levels of oxidative stress.