| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
This study revealed that continuous hypoxic stimulation suppressed the water intake and food intake without a decrease in urinary volume. This result indicates that hypoxia disorders the homeostasis of body fluid balance and the regulation of neurohypophyseal hormone. In addition to the constant mRNA expression of erythropoietin（EPO), known as a hypoxia-responsive hematopoietic cytokine, in the neurohypophysis, immunohistochemical analyses detected the expression of EPO receptor in the areas around the inferior hypophyseal artery, where are rich in axon terminals and pituicytes.
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