A study of bone regeneration by OCP/Collagen combined with MSC
| Project/Area Number |
25870043
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
Surgical dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 骨再生 / リン酸オクタカルシウム / MSC / OCP/Collagen / 幹細胞 |
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| Outline of Final Research Achievements |
This study was designed to confirmed the bone regeneration by octacalcium phosphate (OCP) and collagen composite (OCP/Collagen) with mesenchymal stem cell (MSC) (OCP/Col・MSC). Canine mandibular bone defect was used for bone defect model, however it was difficult to compare the bone regeneration of OCP/Collagen and OCP/Col・MSC, because OCP/Collagen indicated enough bone regeneration in canine mandibular defect. We changed the bone defect model to mandibular segmental defect. It was thought that an evaluation of the bone regeneration ability with OCP/Collagen and OCP/Col・MSC was enabled in new model and we decided to apply as a new study after the next fiscal year again.
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Report
(4 results)
Research Products
(3 results)
