| Project/Area Number |
25870061
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
Structural/Functional materials
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| Research Institution | Tohoku University |
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Principal Investigator |
SATO MITSUTAKA 東北大学, 金属材料研究所, 助教 (10547706)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 抗菌性 / ハイドロキシアパタイト / 水溶液プロセス / X線吸収微細構造 / 抗菌性ハイドロキシアパタイト / XAFS / 格子定数変化 / 溶解性 / 形態制御 / TEM |
|---|
| Outline of Final Research Achievements |
In order to develop novel artificial alternates of our hard tissue which prevent some infections during and after orthopedic surgery, antibacterial element substituted HAp powders were prepared based on the aqueous solution process, and the effect of antibacterial element substitution on the crystal phase, microstructure, antibacterial property and other properties were investigated.
Although it is possible to provide a high antibacterial property to HAp by Ag addition, the solid solution limit of Ag was a very small, and most of the added Ag existed as an Ag metal. In the case of Cu addition, it was possible to substitute about 10 mol% for Ca of HAp, and Cu-substituted HAp sample showed similar antibacterial property to that of Ag-substituted HAp.
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