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Pancreatic ductal anomaly as a biomarker in pancreatitis.

Research Project

Project/Area Number 25870148
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Gastroenterology
Radiation science
Research InstitutionThe University of Tokyo

Principal Investigator

Gonoi Wataru  東京大学, 医学部附属病院, 助教 (60631174)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
KeywordsPancreatic duct / Pancreas / MRI / Anomaly / Pancreatitis / Alcohol / Radiology / Gastroentelogy / pancreatic duct / pancreas divisum / pancreas / anormaly / pancreatitis / radiology / gastroenterology / 膵管 / 膵 / 膵管形態異常 / 膵炎 / anomaly
Outline of Final Research Achievements

The applicant made combined big data of pancreatic ductal MR images and clinical information and investigated the clinical significance of several pancreatic ductal anomalies on pancreatitis or hyperamylasemia/hyperlipasemia. The new findings are as follows: (1) Santorinicele without pancreas divisum pathophysiology is a rare variation associated to chronic pancreatitis (2) ansa pancreatica, one of the rare pancreatic ductal anomalies, is a risk factor for recurrent acute panreatitis, (3) idiopathic hyperamylasemia/hyperlipasemia is related to the existence of pancreas divisum and meandering main pancreatic duct, (4) chronic pancreatitis could cause atrophy of the body and tail of the pancreas.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (28 results)

All 2016 2015 2014 2013 Other

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results) Presentation (21 results) (of which Int'l Joint Research: 4 results,  Invited: 9 results) Book (1 results) Remarks (2 results)

  • [Journal Article] 膵管系の形状異型2016

    • Author(s)
      五ノ井渉、林(山川)高菜、大友邦
    • Journal Title

      画像診断

      Volume: 36 Pages: 393-399

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pancreatic lipoma with a solid nodule mimicking invasion from adjoining intraductal papillary mucinous neoplasm2016

    • Author(s)
      Yoko Namiki, Masako Ikemura, Kuni Ohtomo, Eriko Maeda, Wataru Gonoi, Nobuhisa Akamatsu
    • Journal Title

      Radiology Case Reports

      Volume: in print

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Santorinicele without pancreas divisum pathophysiology: Initial clinical and radiographic investigations.2013

    • Author(s)
      Gonoi W, Akai H, Hagiwara K, Akahane M, Hayashi N, Maeda E, Yoshikawa T, Kiryu S, Tada M, Uno K, Okura N, Koike K, Ohtomo K
    • Journal Title

      BMC gastroenterology

      Volume: 13 Issue: 1 Pages: 62-62

    • DOI

      10.1186/1471-230x-13-62

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Visualization of bile movement using MRI spin-labeling technique: preliminary results.2013

    • Author(s)
      Gonoi W, Akahane M, Watanabe Y, Isono S, Maeda E, Hagiwara K, Ohtomo K
    • Journal Title

      American journal of roentgenology

      Volume: 201 Issue: 1 Pages: 133-141

    • DOI

      10.2214/ajr.12.8928

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] The Voice of EPOS2016

    • Author(s)
      Wataru Gonoi
    • Organizer
      European Congress of Radiology 2016
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2016-03-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Benign postoperative changes of the abdomen and pelvis that may simulate recurrence of malignant tumors.2016

    • Author(s)
      Watadani T, Okura N, Gonoi W, Sato J, Ohtomo K
    • Organizer
      European Congress of Radiology 2016
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2016-03-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Increased incidence of pancreatic cancer in hepatocellular carcinoma cohort Gonoi Wataru, Suzuki Yuichi, Mitsuda Minoru, Matsuda Kanako, Nakai Yosuke, Akahane Masaaki, Nakagawa Keiichi, Miyagawa Kiyoshi, Ohtomo Kuni2016

    • Author(s)
      Gonoi Wataru, Suzuki Yuichi, Mitsuda Minoru, Matsuda Kanako, Nakai Yosuke, Akahane Masaaki, Nakagawa Keiichi, Miyagawa Kiyoshi, Ohtomo Kuni
    • Organizer
      European Congress of Radiology 2016
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2016-03-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Santorinicele with pancreas divisum compared with Santorinicele without pancreas divisum: a cross-sectional study2015

    • Author(s)
      Gonoi W, Akai H, Hagiwara K, Akahane M, Yamakawa T, Hayashi N, Maeda E, Yoshikawa T, Kiryu S, Okura N, Ohtomo K
    • Organizer
      The 36th Turkish Congress of Radiology (TURKRAD 2015)
    • Place of Presentation
      Antalya(Turkey)
    • Year and Date
      2015-10-20
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Santorinicele with pancreas divisum compared with Santorinicele without pancreas divisum: a cross-sectional study2015

    • Author(s)
      Gonoi W, Akai H, Hagiwara K, Akahane M, Yamakawa T, Hayashi N, Maeda E, Yoshikawa T, Kiryu S, Okura N, Ohtomo K
    • Organizer
      Journees Francaises de Radiologie 2015 (JFR 2015)
    • Place of Presentation
      Paris(France)
    • Year and Date
      2015-10-13
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 慢性膵炎では膵尾部側に萎縮が生じる: 健常群と慢性膵炎群の比較2015

    • Author(s)
      山川貴菜、五ノ井渉、吉川健啓、林直人、大友邦
    • Organizer
      第51回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      いわて県民情報交流センター(岩手県・盛岡市)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] 肝細胞癌患者では膵癌が高頻度に併存する:CT被曝の影響は?2015

    • Author(s)
      五ノ井 渉、鈴木 雄一、三津田 実、松田 佳奈子、大熊 ひでみ、山川 貴菜、中井陽介、赤羽 正章、水野 卓、三瀬 葉子、中川 恵一、宮川 清、小池 和彦、大友 邦
    • Organizer
      第51回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      いわて県民情報交流センター(岩手県・盛岡市)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Santorinicele with pancreas divisum compared with Santorinicele without pancreas divisum: a cross-sectional study2015

    • Author(s)
      W Gonoi, H Akai, K Hagiwara, M Akahane, T Yamakawa, N Hayashi, E Maeda, T Yoshikawa, S Kiryu, N Okura, K Ohtomo
    • Organizer
      The 71th Korean Congress of Radiology (KCR 2015)
    • Place of Presentation
      Seoul(Korea)
    • Year and Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] バイエル奨励賞学術報告記2015

    • Author(s)
      五ノ井渉
    • Organizer
      日本腹部放射線学会2015
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2015-06-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Santorinicele with pancreas divisum compared with Santorinicele without pancreas divisum: a cross-sectional study2015

    • Author(s)
      Wataru Gonoi, H. Akai, K Hagiwara, M Akahane, T Yamakawa, N Hayashi, E Maeda, T Yoshikawa, S Kiryu, N Okura, K Ohtomo
    • Organizer
      European Society of Gastrointestinal and Abdominal Radiology (ESGAR 2015)
    • Place of Presentation
      Paris(France)
    • Year and Date
      2015-06-09
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Santorinicele without pancreas divisum pathophysiology (SWOPP): Initial clinical and radiographical investigations2015

    • Author(s)
      Gonoi Wataru, Akai HIroyuki, Hagiwara Kazuchika, Akahane Masaaki, Maeda Eriko, Yoshikawa Takeharu, Kiryu Shigeru, Okura Naoki, Ohtomo Kuni
    • Organizer
      American Roentgen Ray Society (ARRS) 2015
    • Place of Presentation
      Toronto(Canada)
    • Year and Date
      2015-04-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 膵管癒合不全を伴うSantoriniceleと膵管癒合不全を伴わないSantoriniceleの比較:横断的研究2015

    • Author(s)
      五ノ井 渉、赤井宏行、萩原良哉、赤羽正章、山川貴菜、林直人、前田恵理子、吉川健啓、桐生茂、大倉直樹、大友邦
    • Organizer
      第74回 日本医学放射線学会第74回 日本医学放射線学会 総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] Takana Yamakawa, Wataru Gonoi, Takeharu Yoshikawa, Naoto Hayashi, Minoru Tada, Kazuhiko Koike, Kuni Ohtomo2015

    • Author(s)
      Ansa pancreatica as a risk factor for recurrent acute pancreatitis
    • Organizer
      第74回 日本医学放射線学会 総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] 大腸癌肝転移に対する化学療法の意義と効果判定の新しい考え方2015

    • Author(s)
      五ノ井渉
    • Organizer
      Chugai Surgical Oncology Educational Meeting in Tokyo
    • Place of Presentation
      コートヤード・マリオット銀座東武ホテル(東京都・中央区)
    • Year and Date
      2015-04-10
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 膵脂肪腫の2例2014

    • Author(s)
      並木洋子、石田尚利、山川貴菜、五ノ井渉、赤松延久、池村雅子、渡谷岳行、渡辺慎、大友邦
    • Organizer
      第446回日本医学放射線学会 関東地方会定期大会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Santorinicele without pancreas divisum pathophysiology (SWOPP): Initial clinical and radiographical investigations2014

    • Author(s)
      Gonoi Wataru, Akai HIroyuki, Hagiwara Kazuchika, Akahane Masaaki, Maeda Eriko, Yoshikawa Takeharu, Kiryu Shigeru, Okura Naoki, Ohtomo Kuni
    • Organizer
      The 70th Korean Congress of Radiology (KCR 2014)
    • Place of Presentation
      ソウル、韓国
    • Year and Date
      2014-10-08 – 2014-10-11
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Pancreas divisum as a predisposing factor for chronic and recurrent idiopathic pancreatitis: initial in vivo survey2014

    • Author(s)
      Gonoi W, Akai H, Hagiwara K, Akahane M, Hayashi N, Maeda E, Yoshikawa T, Yamakawa T, Tada M, Uno K, Ohtsu H, Koike K, Ohtomo K
    • Organizer
      The 15th Asian Oceanina Congress of Radiology (AOCR 2014)
    • Place of Presentation
      神戸
    • Year and Date
      2014-09-24 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 胆膵病変の有病率:上腹部MRI検診による検討2014

    • Author(s)
      五ノ井 渉
    • Organizer
      第53回消化器がん検診学会
    • Place of Presentation
      福井
    • Year and Date
      2014-06-06 – 2014-06-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 膵管癒合不全を伴わないSantorinicele: 初の臨床的・画像的研究2014

    • Author(s)
      五ノ井 渉、赤井宏行、萩原良哉、赤羽正章、林直人、 前田恵理子、吉川健啓、桐生茂、大倉直樹、大友邦
    • Organizer
      第73回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Meandering main pancreatic duct から生じた false pancreas divisum の1例2013

    • Author(s)
      五ノ井 渉, 赤羽 正章, 多田 稔, 大友 邦
    • Organizer
      第49回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Research-status Report
  • [Presentation] 膵管の画像診断

    • Author(s)
      五ノ井 渉
    • Organizer
      第443回日本医学放射線学会 関東地方会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
    • Invited
  • [Book] CT・MRI “戦略的”活用ガイド2014

    • Author(s)
      五ノ井渉(分担執筆)
    • Total Pages
      432
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Remarks] Researchmap:五ノ井渉

    • URL

      http://researchmap.jp/gonoi/

    • Related Report
      2015 Annual Research Report
  • [Remarks] http://researchmap.jp/gonoi/

    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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