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Development of Knowledge Integrated Database for Clinical Information Retrieval System

Research Project

Project/Area Number 25870156
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical and hospital managemen
Life / Health / Medical informatics
Research InstitutionThe University of Tokyo

Principal Investigator

Kawazoe Yoshimasa  東京大学, 医学部附属病院, 助教 (10621477)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords電子的診療データ / オントロジー / セマンティックウェブ / RDF / SPARQL / Health Level Seven / 診療データの検索 / 臨床試験 / クエリ拡張
Outline of Final Research Achievements

This study aimed to develop a clinical information retrieval system that utilize life-science knowledge resources for query expansion. We developed a generic method to convert HL7 version 2.5 messages into the RDF, and also converted five kinds of existing drug databases into RDF and provided explicit links between the corresponding items among them. With those linked drug data, we then developed a method for query expansion to search the RDF-ized HL7 v2.5 messages using semantic information on drug classes. An evaluation of the proposed method in use case for detecting adverse drug events showed that the execution time of the developed queries increased with the amount of clinical data without diverging.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2016 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results) Remarks (2 results) Funded Workshop (1 results)

  • [Journal Article] A Querying Method over RDF-ized Health Level Seven v2.5 Messages Using Life Science Knowledge Resources2016

    • Author(s)
      Yoshimasa Kawazoe, Takeshi Imai, Kazuhiko Ohe
    • Journal Title

      JMIR Medical Informatics

      Volume: 4(2) Issue: 2 Pages: 0-12

    • DOI

      10.2196/medinform.5275

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Linked DataによるSS-MIX2標準化ストレージの活用に向けて - 薬剤の有害事象検出を目的としたfederation queryの実行可能性の検討 -2014

    • Author(s)
      河添悦昌
    • Organizer
      日本医療情報学会
    • Place of Presentation
      幕張メッセ国際会議場
    • Year and Date
      2014-11-08
    • Related Report
      2014 Research-status Report
  • [Remarks] 診療情報を検索するための新しい設計に基づくデータベース構築に関する研究

    • URL

      http://www.m.u-tokyo.ac.jp/medinfo/wp-content/uploads/2013/08/ethics-20140729.pdf

    • Related Report
      2015 Annual Research Report
  • [Remarks] Linked Drug Database

    • URL

      https://github.com/linked-drug-data/publish

    • Related Report
      2015 Annual Research Report
  • [Funded Workshop] AMIA 2016 Joint Summits on Translational Science2016

    • Place of Presentation
      Parc 55 San Francisco - A Hilton Hotel, 55 Cyril Magnin Street, San Francisco, CA 94102, US
    • Year and Date
      2016-03-21
    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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