Non-equiliblium energy conversion efficiency measurement of molecular motor kinesin
| Project/Area Number |
25870173
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biological physics/Chemical physics/Soft matter physics
Biophysics
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| Research Institution | Kyushu University (2014-2015)
The University of Tokyo (2013) |
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Principal Investigator |
Takayuki Ariga 九州大学, 理学(系)研究科(研究院), 特任准教授 (30452262)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 1分子計測・操作 / 生体物質の物理 / 非平衡物理学 / エネルギー変換 / 生体分子モーター / １分子計測・操作 |
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| Outline of Final Research Achievements |
A large variety of bio-molecular machines are working in cells. Especially, kinesin is walking on the microtubule rail to carry various cargos. We investigated the mechano-chemical efficiencies on the kinesin molecular motor by using a novel non-equilibrium equation through both experimental measurement and simulation approaches. The results showed kinesin's non-equilibrium behaviors and revealed that they do not produce so much futile non-equilibrium dissipation.
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Report
(4 results)
Research Products
(15 results)
