| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
RNA molecules in a cell play very important roles so that genetic information encoded in the genome is instantiated as proteins and exerts actual functions. Three dimensional structure of an RNA is understood by its arrangement of stem structures, and it is important to investigate the properties of this secondary structure to understand the functions of RNAs. In this study, we have succeeded in developing an algorithm (ParasoR) for computing several properties of RNA secondary structures of very long RNAs such as messenger RNAs and long non-coding RNAs for the first time. We have also succeeded in developing an algorithm (CapR) for computing secondary structural context around the binding regions of RNA binding proteins.
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