Analysis of periodontal disease status in aortic aneurysm patients
Project/Area Number |
25870198
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Periodontology
Cardiovascular medicine
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
AOYAMA Norio 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (30611024)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 歯周病 / 歯周病原細菌 / 大動脈瘤 / 循環器疾患 / Periodontal medicine / 感染症 / 炎症 |
Outline of Final Research Achievements |
Periodontitis may be a risk factor for cardiovascular diseases such as abdominal aortic aneurysm. However, the influence of periodontal bacteria on aortic aneurysms is unclear. The aim of this clinical study was to assess periodontal bacterial burden in aortic aneurysm patients. We studied aneurysm patients and age and sex-matched non-aneurysm cardiovascular patients. We measured clinical periodontal parameters and also examined the presence of periodontal bacteria and the antibodies against periodontal bacteria. The aneurysm patients had deeper periodontal pocket than non-aneurysm subjects. The detection rate of periodontal bacteria and the antibody level of periodontal bacteria were comparable between the two groups.
|
Report
(3 results)
Research Products
(7 results)
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[Journal Article] High Incidence of Periodontitis in Japanese Patients With Abdominal Aortic Aneurysm2014
Author(s)
Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M.
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Journal Title
International Heart Journal
Volume: 55
Issue: 3
Pages: 268-270
DOI
NAID
ISSN
1349-2365, 1349-3299
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia.2014
Author(s)
Suzuki JI, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M.
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Journal Title
Heart Vessels
Volume: 掲載確定
Issue: 4
Pages: 498-502
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Incidence of periodontitis in Japanese patients with cardiovascular diseases -A comparison between abdominal aortic aneurysm and arrhythmia.2014
Author(s)
Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M
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Journal Title
Heart Vessels
Volume: 掲載確定
Related Report
Peer Reviewed
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[Journal Article] Periodontitis in Cardiovascular Disease Patients with or without Marfan Syndrome -A Possible Role of Prevotella intermedia2014
Author(s)
Suzuki J, Imai Y, Aoki M, Fujita D, Aoyama N, Tada Y, Wakayama K, Akazawa H, Izumi Y, Isobe M, Komuro I, Nagai R, Hirata Y.
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Journal Title
Plos One
Volume: epub
Issue: 4
Pages: e95521-e95521
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] High Incidence of Periodontitis in Japanese Patients With Abdominal Aortic Aneurysm2014
Author(s)
Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M.
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Journal Title
NAID
Related Report
Peer Reviewed
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