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Non-invasive and quantitative measurement of dental pulp viability using multiple wavelength Transmitted-light plethysmography (TLP)

Research Project

Project/Area Number 25870201
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Orthodontics/Pediatric dentistry
Conservative dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Kakino Satoko  東京医科歯科大学, 歯学部附属病院, 助教 (30516307)

Co-Investigator(Renkei-kenkyūsha) MATSUURA Yuji  東北大学, 大学院医工学研究科, 教授 (10241530)
MIWA Zenzo  東京医科歯科大学, 歯学部附属病院, 講師 (30157705)
Research Collaborator AZUSA Yamada  東北大学, 大学院医工学研究科, 大学院生
GANBOLD Khongorzul  東京医科歯科大学, 大学院医歯学総合研究科, 大学院生
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords歯髄診断 / 歯髄血液 / 酸素飽和度 / 歯髄炎 / 電気歯髄診 / 幼若永久歯 / 電気歯髄診断
Outline of Final Research Achievements

Transmitted-light plethysmography (TLP) is a non-invasive objective method that uses a 525-nm LED to detect blood volume change in the pulp. Previous study showed that TLP amplitude is influenced by multiple factors, such as pathological conditions, tooth morphology, dental pulp circulating system, blood oxygen saturation, and so on. The present study aimed to investigate pulpal blood flow with TLP in healthy permanent maxillary incisors in different root formation stages and to assess the influences of body growth of children and tooth color on the TLP amplitude. The results indicated that the TLP amplitude and optical density may be affected by growth and development in children, thus indicating changes in the vascular dynamics of the pulp and hard tissue maturation during root formation stages.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2016 2015 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] LEDを利用した透過型光電脈波法(TLP)の歯髄診断への応用2014

    • Author(s)
      柿野聡子、三輪全三
    • Journal Title

      日本レーザー歯学会誌

      Volume: 25 Pages: 153-158

    • NAID

      130004852516

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Relevance of pulpal blood flow and root development of young permanent teeth measured by Transmitted-light Plethysmography (TLP)2016

    • Author(s)
      Ganbold K, Kakino S, Matsuura Y, Matoba K, Miyashin M
    • Organizer
      10th Biennial Conference of the Pediatric Dentistry Association of Asia
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-05-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Quantitative diagnosis for dental pulp viability relevant to blood supply2015

    • Author(s)
      S.Kakino, Z.Miwa, M.Miyashin, D.Sakota, K.Matoba
    • Organizer
      IADR
    • Place of Presentation
      Boston, USA
    • Year and Date
      2015-03-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 透過型光電脈波法による歯髄血流測定 ―小児期外傷歯の歯髄診断への応用―

    • Author(s)
      柿野聡子
    • Organizer
      第6回レーザー学会 レーザーバイオ医療技術専門委員会
    • Place of Presentation
      仙台
    • Related Report
      2013 Research-status Report
    • Invited

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Published: 2014-07-25   Modified: 2019-07-29  

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